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从比特到床边：心脏电生理学进入数字孪生时代。

From bits to bedside: entering the age of digital twins in cardiac electrophysiology.

作者信息

Bhagirath Pranav, Strocchi Marina, Bishop Martin J, Boyle Patrick M, Plank Gernot

机构信息

Department of Cardiology, Amsterdam University Medical Center, Meibergdreef 9, Amsterdam, 1105 AZ, The Netherlands.

School of Biomedical Engineering and Imaging Sciences, King's College London, SE1 7EH London, UK.

出版信息

Europace. 2024 Dec 3;26(12). doi: 10.1093/europace/euae295.

DOI:10.1093/europace/euae295
PMID:39688585
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11649999/
Abstract

This State of the Future Review describes and discusses the potential transformative power of digital twins in cardiac electrophysiology. In this 'big picture' approach, we explore the evolution of mechanistic modelling based digital twins, their current and immediate clinical applications, and envision a future where continuous updates, advanced calibration, and seamless data integration redefine clinical practice of cardiac electrophysiology. Our aim is to inspire researchers and clinicians to embrace the extraordinary possibilities that digital twins offer in the pursuit of precision medicine.

摘要

本《未来状况综述》描述并讨论了数字孪生在心脏电生理学中的潜在变革力量。采用这种“宏观视角”的方法，我们探索基于机制建模的数字孪生的发展历程、它们当前及近期的临床应用，并设想一个通过持续更新、先进校准和无缝数据集成来重新定义心脏电生理临床实践的未来。我们的目标是激励研究人员和临床医生接受数字孪生在追求精准医学过程中所带来的非凡可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a064/11649999/0c19c7501c77/euae295f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a064/11649999/9de55bb3c6ae/euae295_ga.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a064/11649999/0c6e07f6334d/euae295f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a064/11649999/0c50d2524502/euae295f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a064/11649999/d1e9ffbb87e6/euae295f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a064/11649999/0c19c7501c77/euae295f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a064/11649999/9de55bb3c6ae/euae295_ga.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a064/11649999/0c6e07f6334d/euae295f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a064/11649999/0c50d2524502/euae295f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a064/11649999/d1e9ffbb87e6/euae295f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a064/11649999/0c19c7501c77/euae295f4.jpg

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