Osborn M F, Johnson A P, Taylor-Robinson D
Genitourin Med. 1985 Aug;61(4):244-6. doi: 10.1136/sti.61.4.244.
The ability of a panel of normal human serum samples to inactivate 12 strains of Chlamydia trachomatis, each of a different serovar, was investigated. A wide range of antichlamydial activity was observed, with survival rates of C trachomatis varying from less than 1% in some experiments to 100% in others. The strain specificity of the anti-chlamydial activity exhibited by individual serum samples was not, however, related to the antigenic cross reactivity between serovars demonstrable by microimmunofluorescence testing, which suggested that type specific antigens were not predominantly involved in the inactivation process.
研究了一组正常人血清样本灭活12株沙眼衣原体(每株血清型不同)的能力。观察到抗衣原体活性范围广泛,沙眼衣原体的存活率在某些实验中低于1%,而在其他实验中则为100%。然而,单个血清样本所表现出的抗衣原体活性的菌株特异性与通过微量免疫荧光试验可证明的血清型之间的抗原交叉反应性无关,这表明型特异性抗原在灭活过程中并非主要起作用。