Ortqvist A, Sterner G, Nilsson J A
Scand J Infect Dis. 1985;17(4):377-86. doi: 10.3109/13813458509058778.
53 patients with community-acquired pneumonia requiring treatment in an Intensive Care Unit (ICU) were studied retrospectively. The majority of patients (77%) had some predisposing factor: illness, smoking or alcoholism. A cause of pneumonia was established in 53% of the cases; Streptococcus pneumoniae was the dominating pathogen. Immediate active treatment was required in 70% of the patients and 58% were treated with mechanical ventilation. The overall mortality was 25% (32% among patients treated with mechanical ventilation) and rose to 39% when a follow-up period of 3.25 years on average was included. A significantly higher mortality rate was seen among elderly patients and among those who were previously immunocompromised or who had a leukocyte count of less than or equal to 9 X 10(9)/l on admission to hospital. It is concluded that although the mortality rate was considerable among the 53 ICU-treated patients with severe community-acquired pneumonias, several were saved by intensive care treatment. Most of those who survived their pneumonia eventually recovered fully.
对53例需要在重症监护病房（ICU）接受治疗的社区获得性肺炎患者进行了回顾性研究。大多数患者（77%）有一些易感因素：疾病、吸烟或酗酒。53%的病例确定了肺炎病因；肺炎链球菌是主要病原体。70%的患者需要立即进行积极治疗，58%的患者接受了机械通气治疗。总体死亡率为25%（接受机械通气治疗的患者中为32%），当平均纳入3.25年的随访期时，死亡率升至39%。老年患者以及入院时曾免疫功能低下或白细胞计数小于或等于9×10⁹/L的患者死亡率明显更高。结论是，尽管在这53例接受ICU治疗的重症社区获得性肺炎患者中死亡率相当高，但重症监护治疗挽救了一些患者的生命。大多数肺炎幸存者最终完全康复。
