Farinetti Alberto, Manenti Antonio, Cocchi Camilla, Mattioli Anna Vittoria
Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy.
University "Cattolica del Sacro Cuore", Rome, Italy.
J Geriatr Cardiol. 2025 Aug 28;22(8):736-745. doi: 10.26599/1671-5411.2025.08.001.
Caffeine is a widely consumed stimulant known for its cardiovascular and metabolic effects. However, its impact on cardiovascular risk, including arrhythmias, in older adults remains underexplored. Emerging evidence highlights sex-specific differences in caffeine metabolism, which may influence its role in cardiovascular health. This perspective examines the interaction between caffeine, hormonal changes, metabolic processes, and lifestyle factors, focusing on older women compared to men. Understanding these differences is essential for tailoring dietary and clinical recommendations to mitigate cardiovascular risks and promote healthy aging.
咖啡因是一种广泛消费的兴奋剂，以其对心血管和代谢的影响而闻名。然而，其对老年人心血管风险（包括心律失常）的影响仍未得到充分研究。新出现的证据突出了咖啡因代谢中的性别差异，这可能会影响其在心血管健康中的作用。本文从性别视角审视咖啡因、激素变化、代谢过程和生活方式因素之间的相互作用，重点关注老年女性与男性的差异。了解这些差异对于制定饮食和临床建议以降低心血管风险和促进健康老龄化至关重要。
