胸腔积液中pH值、乳酸脱氢酶、乳酸和葡萄糖的诊断意义

Diagnostic significance of pH, lactic acid dehydrogenase, lactate and glucose in pleural fluid.

作者信息

Chavalittamrong B, Angsusingha K, Tuchinda M, Habanananda S, Pidatcha P, Tuchinda C

出版信息

Respiration. 1979;38(2):112-20. doi: 10.1159/000194067.

DOI:10.1159/000194067

Abstract

The pH, lactic acid dehydrogenase, lactate and glucose of pleural fluid simultaneous with serum lactic acid dehydrogenase, blood lactate and glucose were determined in 105 pediatric patients. The patients were classified into groups according to the diagnosis. The pleural fluid of empyema cases was found to have the lowest pH with a mean value of 6.83 (p less than 0.0075). The malignant pleural fluid has a relatively low pH with a mean value of 7.32. The lactic acid dehydrogenase in pleural fluid of empyema cases has the highest mean of 1,470.68 (p less than 0.05). The lactic acid dehydrogenase was found increased in malignancy, tuberculosis and parapneumonic effusion cases. Lactate level was found extremely high in empyema cases with a mean value of 13.68. It was also found extremely high in malignancy, tuberculosis and parapneumonic effusion cases. The glucose level was markedly decreased in empyema cases. There exists correlation of pleural fluid lactate to pH, lactic acid dehydrogenase and glucose, as well as that of pH to lactic acid dehydrogenase.

摘要

对105例儿科患者同时测定了胸水的pH值、乳酸脱氢酶、乳酸和葡萄糖，以及血清乳酸脱氢酶、血乳酸和血糖。根据诊断将患者分组。发现脓胸病例的胸水pH值最低，平均值为6.83（p<0.0075）。恶性胸水的pH值相对较低，平均值为7.32。脓胸病例胸水的乳酸脱氢酶平均值最高，为1470.68（p<0.05）。在恶性肿瘤、结核和类肺炎性胸腔积液病例中发现乳酸脱氢酶升高。脓胸病例的乳酸水平极高，平均值为13.68。在恶性肿瘤、结核和类肺炎性胸腔积液病例中也发现其极高。脓胸病例的葡萄糖水平明显降低。胸水乳酸与pH值、乳酸脱氢酶和葡萄糖之间存在相关性，pH值与乳酸脱氢酶之间也存在相关性。