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酿酒酵母完整细胞在与低浓度亚硫酸盐孵育后ATP含量迅速下降。

Rapid decrease of ATP content in intact cells of Saccharomyces cerevisiae after incubation with low concentrations of sulfite.

作者信息

Schimz K L, Holzer H

出版信息

Arch Microbiol. 1979 Jun;121(3):225-9. doi: 10.1007/BF00425059.

DOI:10.1007/BF00425059
PMID:42368
Abstract

Sulfite, at concentrations above 1 mM and at a pH below 4, caused cell death in Saccharomyces cerevisiae X2180 as measured by the colony-forming capacity. A rapid decrease in the ATP content was observed prior to cellular death. The depletion of ATP was reversible and the lethal effect could be prevented if the cells were exposed to sulfite for periods of less than 1 h. Extent and rate of ATP depletion were dependent on time, pH value, temperature and sulfite concentrations.

摘要

亚硫酸盐在浓度高于1 mM且pH值低于4时,通过集落形成能力测定,会导致酿酒酵母X2180细胞死亡。在细胞死亡之前观察到ATP含量迅速下降。ATP的消耗是可逆的,如果细胞暴露于亚硫酸盐的时间少于1小时,致死效应可以得到预防。ATP消耗的程度和速率取决于时间、pH值、温度和亚硫酸盐浓度。

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