Burrows R, Mann J A, Goodridge D
J Hyg (Lond). 1974 Feb;72(1):135-43. doi: 10.1017/s0022172400023305.
Pigs exposed to relatively small amounts of virus by intradermal inoculation of the feet or by skin sacrification developed clinical disease. Large amounts of virus were recovered from samples taken from the nose, mouth, pharynx, rectum and the prepuce or vagina during the first week of infection and smaller amounts during the second week. Virus was recovered from the faeces of most animals 16 days after infection and from one animal for 23 days. Pigs in contact with inoculated animals were killed at intervals before the appearance of clinical disease. The distribution and amounts of virus in various tissues indicated that infection has most likely gained entry through the skin or the epithelia and mucosae of the digestive tract. Some pigs acquired subclinical infections in which no virus excretion was detected and no transmission of infection to susceptible pigs took place over a period of 5 weeks.
通过足部皮内接种或皮肤划破接种接触相对少量病毒的猪出现了临床疾病。在感染的第一周，从鼻、口、咽、直肠以及包皮或阴道采集的样本中可检测到大量病毒，第二周病毒量较少。大多数动物在感染16天后粪便中可检测到病毒，一只动物在23天内粪便中均可检测到病毒。在出现临床疾病之前，定期处死与接种动物接触的猪。病毒在各种组织中的分布和数量表明，感染很可能是通过皮肤或消化道的上皮和黏膜进入的。一些猪发生了亚临床感染，在此期间未检测到病毒排泄，且在5周内未将感染传播给易感猪。
