组织相容性不相容的T淋巴细胞与B淋巴细胞之间的细胞相互作用。VI. 源自H-2复合体S区和D区基因不同的小鼠供体品系的淋巴细胞之间的协同反应。
Cell interactions between histoincompatible T and B lymphocytes. VI. Cooperative responses between lymphocytes derived from mouse donor strains differing at genes in the S and D regions of the H-2 complex.
作者信息
Katz D H, Dorf M E, Benacerraf B
出版信息
J Exp Med. 1974 Jul 1;140(1):290-5. doi: 10.1084/jem.140.1.290.
Abstract
In our initial studies on the question of histocompatibility requirements in T-B-cell interactions, we found that no cooperation occurred with mixtures of T and B cells from BALB/c (H-2(d)) and A/J (H-2(a)) donors, respectively (1). These particular strains are identical for genes in the S and D regions of the H-2 complex but possess major differences at the K-end. Many differences are known to exist in the I region as well. Thus, these early data indicated that gene identities only at the D-end are insufficient to permit optimal cooperative interactions to occur under these conditions.
摘要
在我们关于T细胞与B细胞相互作用中组织相容性要求问题的初步研究中，我们发现分别来自BALB/c（H-2(d)）和A/J（H-2(a)）供体的T细胞和B细胞混合物之间没有发生协同作用（1）。这两个特定品系在H-2复合体的S区和D区的基因是相同的，但在K端存在主要差异。已知在I区也存在许多差异。因此，这些早期数据表明，在这些条件下，仅在D端的基因相同不足以允许最佳协同相互作用发生。
相似文献
1
Cell interactions between histoincompatible T and B lymphocytes. VI. Cooperative responses between lymphocytes derived from mouse donor strains differing at genes in the S and D regions of the H-2 complex.组织相容性不相容的T淋巴细胞与B淋巴细胞之间的细胞相互作用。VI. 源自H-2复合体S区和D区基因不同的小鼠供体品系的淋巴细胞之间的协同反应。
J Exp Med. 1974 Jul 1;140(1):290-5. doi: 10.1084/jem.140.1.290.
2
Cell interactions between histoincompatible T and B lymphocytes. II. Failure of physiologic cooperative interactions between T and B lymphocytes from allogeneic donor strains in humoral response to hapten-protein conjugates.组织相容性不相容的T淋巴细胞和B淋巴细胞之间的细胞相互作用。II. 来自同种异体供体品系的T淋巴细胞和B淋巴细胞在对半抗原-蛋白质结合物的体液反应中缺乏生理性协同相互作用。
J Exp Med. 1973 Jun 1;137(6):1405-18. doi: 10.1084/jem.137.6.1405.
3
Cell interactions between histoincompatible T and B lymphocytes. VII. Cooperative responses between lymphocytes are controlled by genes in the I region of the H-2 complex.组织相容性不相容的T淋巴细胞和B淋巴细胞之间的细胞相互作用。VII.淋巴细胞之间的协同反应受H-2复合体I区基因的控制。
J Exp Med. 1975 Jan 1;141(1):263-8. doi: 10.1084/jem.141.1.263.
4
Histocompatibility and T-B cell cooperation in mouse radiation chimeras.小鼠辐射嵌合体中的组织相容性与T细胞和B细胞协作
J Immunol. 1975 Dec;115(6):1607-12.
5
Cell interactions between histoincompatible T and B lymphocytes. The H-2 gene complex determines successful physiologic lymphocyte interactions.组织相容性不相容的T淋巴细胞与B淋巴细胞之间的细胞相互作用。H-2基因复合体决定淋巴细胞间成功的生理相互作用。
Proc Natl Acad Sci U S A. 1973 Sep;70(9):2624-8. doi: 10.1073/pnas.70.9.2624.
6
Activation of T and B lymphocytes in vitro. III. Presence of Ia determinants on allogeneic effect factor.T和B淋巴细胞的体外激活。III. 同种异体效应因子上Ia决定簇的存在。
J Exp Med. 1974 Dec 1;140(6):1717-22. doi: 10.1084/jem.140.6.1717.
7
Evidence for identity or close association of the Fc receptor of B lymphocytes and alloantigens determined by the Ir region of the H-2 complex.关于B淋巴细胞的Fc受体与由H-2复合体的Ir区域所决定的同种异体抗原的同一性或紧密关联的证据。
J Exp Med. 1974 Sep 1;140(3):779-96. doi: 10.1084/jem.140.3.779.
8
Cell interactions between histoincompatible T and B lymphocytes. I. Allogeneic effect by irradiated host T cells on adoptively transferred histoincompatible B lymphocytes.组织相容性不相容的T淋巴细胞与B淋巴细胞之间的细胞相互作用。I. 受照射宿主T细胞对过继转移的组织相容性不相容B淋巴细胞的同种异体效应。
J Exp Med. 1973 Jun 1;137(6):1393-404. doi: 10.1084/jem.137.6.1393.
9
Hapten-specific IgE antibody responses in mice. II. Cooperative interactions between adoptively transferred T and B lymphocytes in the development of IgE response.小鼠对半抗原特异性的IgE抗体应答。II. IgE应答发育过程中过继转移的T淋巴细胞与B淋巴细胞之间的协同相互作用。
J Exp Med. 1973 Sep 1;138(3):538-56. doi: 10.1084/jem.138.3.538.
引用本文的文献
1
Activation of T and B lymphocytes in vitro. III. Presence of Ia determinants on allogeneic effect factor.T和B淋巴细胞的体外激活。III. 同种异体效应因子上Ia决定簇的存在。
J Exp Med. 1974 Dec 1;140(6):1717-22. doi: 10.1084/jem.140.6.1717.
2
Cell interactions between histoincompatible T and B lymphocytes. VII. Cooperative responses between lymphocytes are controlled by genes in the I region of the H-2 complex.组织相容性不相容的T淋巴细胞和B淋巴细胞之间的细胞相互作用。VII.淋巴细胞之间的协同反应受H-2复合体I区基因的控制。
J Exp Med. 1975 Jan 1;141(1):263-8. doi: 10.1084/jem.141.1.263.
3
Helper function of T cells depleted of alloantigen-reactive lymphocytes by filtration through irradiated F1 hybrid recipients. I. Failure to collaborate with allogeneic B cells in a secondary response to sheep erythrocytes measured in vivo.通过照射过的F1杂交受体过滤去除同种异体抗原反应性淋巴细胞的T细胞的辅助功能。I. 在体内测量的对绵羊红细胞的二次反应中无法与同种异体B细胞协作。
J Exp Med. 1976 Sep 1;144(3):617-26. doi: 10.1084/jem.144.3.617.
4
In vitro generation of tumor-specific cytotoxic lymphocytes. Secondary allogeneic mixed tumor lymphocyte culture of normal murine spleen cells.肿瘤特异性细胞毒性淋巴细胞的体外生成。正常小鼠脾细胞的二次同种异体混合肿瘤淋巴细胞培养。
J Exp Med. 1977 Aug 1;146(2):468-82. doi: 10.1084/jem.146.2.468.
5
Regulatory mechanisms in cell-mediated immune responses. II. A genetically restricted suppressor of mixed lymphocyte reactions released by alloantigen-activated spleen cells.细胞介导免疫反应中的调节机制。II. 同种异体抗原激活的脾细胞释放的混合淋巴细胞反应的基因限制抑制因子。
J Exp Med. 1975 Dec 1;142(6):1391-1402. doi: 10.1084/jem.142.6.1391.
6
Bifunctional major histocompatibility-linked genetic regulation of cell-mediated lympholysis to trinitrophenyl-modified autologous lymphocytes.对三硝基苯修饰的自体淋巴细胞的细胞介导淋巴细胞溶解的双功能主要组织相容性连锁基因调控。
J Exp Med. 1975 Oct 1;142(4):914-27. doi: 10.1084/jem.142.4.914.
7
Collaboration of histoincompatible T and B lymphocytes using cells from tetraparental bone marrow chimeras.利用四亲代骨髓嵌合体的细胞实现组织不相容的T淋巴细胞和B淋巴细胞的协作。
J Exp Med. 1975 Oct 1;142(4):989-97. doi: 10.1084/jem.142.4.989.
本文引用的文献
1
Immunization of dissociated spleen cell cultures from normal mice.对来自正常小鼠的脾细胞解离培养物进行免疫接种。
J Exp Med. 1967 Sep 1;126(3):423-42. doi: 10.1084/jem.126.3.423.
2
Antitrinitrophenyl (TNP) plaque assay. Primary response of Balb/c mice to soluble and particulate immunogen.抗三硝基苯基（TNP）空斑试验。Balb/c小鼠对可溶性和颗粒性免疫原的初次反应。
Proc Soc Exp Biol Med. 1969 Nov;132(2):575-81. doi: 10.3181/00379727-132-34264.
3
Genetic control of immune responses in vitro. IV. Conditions for cooperative interactions between nonresponder parental B cells and primed (responder plus nonresponder) F1 T cells in the development of an antibody response under Ir gene control in vitro.体外免疫反应的遗传控制。IV. 在体外Ir基因控制下抗体反应发生过程中，无反应亲代B细胞与致敏（有反应加无反应）F1 T细胞之间协同相互作用的条件。
J Exp Med. 1974 Jul 1;140(1):185-98. doi: 10.1084/jem.140.1.185.
4
Cell interactions between histoincompatible T and B lymphocytes. IV. Involvement of the immune response (Ir) gene in the control of lymphocyte interactions in responses controlled by the gene.组织相容性不相容的T淋巴细胞与B淋巴细胞之间的细胞相互作用。IV. 免疫反应（Ir）基因在由该基因控制的反应中对淋巴细胞相互作用的控制作用。
J Exp Med. 1973 Sep 1;138(3):734-9. doi: 10.1084/jem.138.3.734.
5
Hapten-specific IgE antibody responses in mice. I. Secondary IgE responses in irradiated recipients of syngeneic primed spleen cells.小鼠对半抗原特异性的IgE抗体反应。I. 同基因致敏脾细胞照射受体中的二次IgE反应。
J Exp Med. 1973 Jul 1;138(1):306-11. doi: 10.1084/jem.138.1.306.
6
New lymphocyte antigen system (Lna) controlled by the Ir region of the mouse H-2 complex.由小鼠H-2复合体的Ir区域控制的新淋巴细胞抗原系统（Lna）。
Proc Natl Acad Sci U S A. 1973 Sep;70(9):2509-14. doi: 10.1073/pnas.70.9.2509.
7
The allogeneic effect on immune responses: model for regulatory influences of T lymphocytes on the immune system.同种异体对免疫反应的影响：T淋巴细胞对免疫系统调节作用的模型
Transplant Rev. 1972;12:141-79. doi: 10.1111/j.1600-065x.1972.tb00055.x.
8
The allogeneic effect in inbred mice. II. Establishment of the cellular interactions required for enhancement of antibody production by the graft-versus-host reaction.近交系小鼠中的同种异体效应。II. 建立移植物抗宿主反应增强抗体产生所需的细胞相互作用。
J Exp Med. 1972 Sep 1;136(3):455-65. doi: 10.1084/jem.136.3.455.
9
10
Activation of T and B lymphocytes in vitro. I. Regulatory influence of bacterial lipopolysaccharide (LPS) on specific T-cell helper function.T和B淋巴细胞的体外激活。I. 细菌脂多糖（LPS）对特异性T细胞辅助功能的调节作用。
J Exp Med. 1974 Jan 1;139(1):24-43. doi: 10.1084/jem.139.1.24.
Zotero 插件