西咪替丁预防胃溃疡复发。
Cimetidine in the prevention of gastric ulcer relapse.
作者信息
Machell R J, Ciclitira P J, Farthing M J, Dick A P, Hunter J O
出版信息
Postgrad Med J. 1979 Jun;55(644):393-5. doi: 10.1136/pgmj.55.644.393.
Abstract
Twenty-five patients with healed gastric ulcers completed an 11-month double-blind controlled trial comparing cimetidine 1 g daily with placebo in the prevention of ulcer relapse. Ulcers recurred in 14 patients, 12 on placebo, 2 on cimetidine. In 11 patients, 9 on cimetidine, 2 on placebo, the ulcers remained healed at the end of the trial (P less than 0.002). Cimetidine 1 g daily significantly reduces the relapse rate in gastric ulceration.
摘要
25例胃溃疡已愈合的患者完成了一项为期11个月的双盲对照试验，比较每日1克西咪替丁与安慰剂预防溃疡复发的效果。14例患者溃疡复发，其中12例服用安慰剂，2例服用西咪替丁。11例患者溃疡未复发，其中9例服用西咪替丁，2例服用安慰剂（P<0.002）。每日1克西咪替丁可显著降低胃溃疡的复发率。
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本文引用的文献
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