Bingham S, Williams D R, Cole T J, James W P
Br J Cancer. 1979 Sep;40(3):456-63. doi: 10.1038/bjc.1979.201.
The relationship between food intake and cancer of the large bowel was assessed by calculating the average intakes of foods, nutrients and dietary fibre in the different regions of Great Britain and relating these to the regional pattern of death from colon and rectal cancers between 1969 and 1973. No significant associations were found with the consumption of fat, animal protein or beer, nor with current estimates of total dietary fibre intake. Average intakes of the pentose fraction of total dietary fibres, and of vegetables other than potatoes, were negatively correlated with the truncated age- and sex-standardized death rates from colon cancer (r = -0.960 and -0.940). Specific components of dietary fibre may therefore inhibit colon carcinogenesis.
通过计算英国不同地区食物、营养素和膳食纤维的平均摄入量，并将这些摄入量与1969年至1973年间结肠癌和直肠癌的区域死亡模式相关联，评估了食物摄入量与大肠癌之间的关系。未发现与脂肪、动物蛋白或啤酒的摄入量以及目前膳食纤维总摄入量的估计值存在显著关联。总膳食纤维的戊糖部分以及除土豆以外的蔬菜的平均摄入量与结肠癌的截断年龄和性别标准化死亡率呈负相关（r = -0.960和-0.940）。因此，膳食纤维的特定成分可能会抑制结肠癌的发生。
