慢性活动性肝病中e抗原和抗体的表现。与乙肝抗原-抗体系统及预后的关系。
Behaviour of e antigen and antibody during chronic active liver disease. Relation to HB antigen-antibody system and prognosis.
作者信息
Vogten A J, Summerskill W H, Gitnick G L, Schalm S W, Smith J L, Murphy B L, Maynard J E
出版信息
Lancet. 1976 Jul 17;2(7977):126-8. doi: 10.1016/s0140-6736(76)92849-x.
PMID:59188
Abstract
Serial determinations of e antigen and e antibody were made in 20 patients with chronic active liver disease and hepatitis-B surface antigen (HBsAg) or antibody (anti-HBs). The presence of e antigen was associated with failure to clear HBsAg, produce anti-HBs, or respond to treatment with steroids. It is proposed that the presence of the e antigen is associated with impaired host immune responses to hepatitis-B virus infection and a poor prognosis.
摘要
对20例慢性活动性肝病患者以及乙肝表面抗原（HBsAg）或抗体（抗-HBs）进行了e抗原和e抗体的系列测定。e抗原的存在与无法清除HBsAg、产生抗-HBs或对类固醇治疗无反应相关。有人提出，e抗原的存在与宿主对乙肝病毒感染的免疫反应受损及预后不良有关。
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