Gibson P E, Ruparella K
J Clin Pathol. 1977 Oct;30(10):925-7. doi: 10.1136/jcp.30.10.925.
The occurrence of e antigen in 44 patients with acute hepatitis B was studied in order to determine if e was related to the outcome of the illness. In 13.6% of cases e was detected, and in none of these did the carrier state develop. The HBsAg carrier state developed in 4.6% of the patients and in none of these was e antigen detected. Anti-e was detected in only three cases. Only in the very early acute phase of illness e was detected and the time serum samples were taken for the detection of e was considered to be very significant. The occurrence of e was not found to affect the duration of HBs antigenaemia in those patients who recovered completely.
对44例急性乙型肝炎患者进行了e抗原出现情况的研究,以确定e抗原是否与疾病的转归有关。在13.6%的病例中检测到了e抗原,且这些病例均未发展为携带者状态。4.6%的患者发展为HBsAg携带者状态,且这些患者均未检测到e抗原。仅在3例中检测到了抗e。仅在疾病的极早期检测到了e抗原,且采集血清样本检测e抗原的时间被认为非常重要。在完全康复的患者中,未发现e抗原的出现会影响HBs抗原血症的持续时间。