Matsui Y, Noda M, Kohara T
Jpn J Antibiot. 1984 Dec;37(12):2320-7.
Ceftriaxone (Ro 13-9904, CTRX) was studied about the tissue transfer in the gyneco-obstetric field and the following results were obtained. The transfer of CTRX into the uterine tissues and adnexa was favorable following an intravenous injection with 1 g. The mean serum level 1 hour after administration was 123.3 micrograms/ml while the tissue level ranged from 26 to 48 micrograms/g. The level in the pelvic dead space exudate reached a peak 3 to 6 hours after administration and got higher than the serum level at 5 to 6 hours.
研究了头孢曲松(Ro 13 - 9904,CTRX)在妇产科领域的组织转移情况,获得了以下结果。静脉注射1克后,CTRX向子宫组织和附件的转移情况良好。给药后1小时的平均血清水平为123.3微克/毫升,而组织水平在26至48微克/克之间。盆腔死腔渗出液中的水平在给药后3至6小时达到峰值,并在5至6小时高于血清水平。