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相似文献

1
Amino-terminal amino acid sequence of human leukocyte interferon.人白细胞干扰素的氨基末端氨基酸序列
Proc Natl Acad Sci U S A. 1980 Sep;77(9):5102-4. doi: 10.1073/pnas.77.9.5102.
2
Amino acid sequence of a human leukocyte interferon.一种人白细胞干扰素的氨基酸序列。
Proc Natl Acad Sci U S A. 1981 Oct;78(10):6186-90. doi: 10.1073/pnas.78.10.6186.
3
Purification and characterization of human leukocyte interferons by high-performance liquid chromatography.
Methods Enzymol. 1981;78(Pt A):464-72. doi: 10.1016/0076-6879(81)78157-6.
4
Human leukocyte interferon: isolation and characterization of several molecular forms.人白细胞干扰素：几种分子形式的分离与特性
Arch Biochem Biophys. 1981 Aug;210(1):307-18. doi: 10.1016/0003-9861(81)90194-6.
5
Purification and molecular characterization of human fibroblast interferon.人成纤维细胞干扰素的纯化及分子特性分析
Arch Biochem Biophys. 1981 Feb;206(2):432-50. doi: 10.1016/0003-9861(81)90111-9.
6
Purification of the interferons.
Pharmacol Ther. 1985;29(3):299-319. doi: 10.1016/0163-7258(85)90006-3.
7
Human leukocyte interferon: production, purification to homogeneity, and initial characterization.人白细胞干扰素：生产、纯化至均一性及初步特性鉴定
Proc Natl Acad Sci U S A. 1979 Feb;76(2):640-4. doi: 10.1073/pnas.76.2.640.
8
Purification and characterization of interferons from a continuous myeloblastic cell line.来自连续髓母细胞系的干扰素的纯化与特性分析
J Biol Chem. 1982 Apr 25;257(8):4071-6.
9
Rapid purification of leukocyte interferons by high-performance liquid chromatography.
J Chromatogr. 1983 Aug 26;266:249-56. doi: 10.1016/s0021-9673(01)90898-2.
10
Purification and characterization of recombinant human leukocyte interferon (IFLrA) with monoclonal antibodies.利用单克隆抗体对重组人白细胞干扰素（IFLrA）进行纯化与特性鉴定
J Biol Chem. 1981 Sep 25;256(18):9750-4.

引用本文的文献

1
Regulation of synthesis of complement protein C4 in human fibroblasts: cell- and gene-specific effects of cytokines and lipopolysaccharide.人成纤维细胞中补体蛋白C4合成的调节：细胞因子和脂多糖的细胞及基因特异性作用。
Immunology. 1994 Aug;82(4):509-15.
2
Augmentation of natural and antibody-dependent cell-mediated cytotoxicity by pure human leukocyte interferon.纯人白细胞干扰素增强自然及抗体依赖的细胞介导的细胞毒性作用。
J Clin Immunol. 1981 Jul;1(3):149-53. doi: 10.1007/BF00922756.
3
Amino acid sequence of a human leukocyte interferon.一种人白细胞干扰素的氨基酸序列。
Proc Natl Acad Sci U S A. 1981 Oct;78(10):6186-90. doi: 10.1073/pnas.78.10.6186.
4
Production of high levels of human leukocyte interferon from a continuous human myeloblast cell culture.从人成髓细胞连续培养物中产生高水平的人白细胞干扰素。
Antimicrob Agents Chemother. 1981 Jul;20(1):5-9. doi: 10.1128/AAC.20.1.5.
5
Production of hybridomas secreting monoclonal antibodies to the human leukocyte interferons.
Proc Natl Acad Sci U S A. 1981 Mar;78(3):1848-52. doi: 10.1073/pnas.78.3.1848.
6
Construction and identification of bacterial plasmids containing nucleotide sequence for human leukocyte interferon.含人白细胞干扰素核苷酸序列细菌质粒的构建与鉴定
Proc Natl Acad Sci U S A. 1980 Dec;77(12):7010-3. doi: 10.1073/pnas.77.12.7010.
7
Evidence for a unique human fibroblast interferon (IFN-beta 1) chromosomal gene, devoid of intervening sequences.关于一种独特的人类成纤维细胞干扰素（IFN-β1）染色体基因的证据，该基因无间隔序列。
Nucleic Acids Res. 1981 Feb 11;9(3):461-71. doi: 10.1093/nar/9.3.461.
8
NH2-terminal amino acid sequence of human fibroblast interferon.人成纤维细胞干扰素的氨基末端氨基酸序列
Proc Natl Acad Sci U S A. 1980 Oct;77(10):5716-9. doi: 10.1073/pnas.77.10.5716.
9
Oncostatin M: a growth regulator produced by differentiated histiocytic lymphoma cells.抑瘤素M：一种由分化型组织细胞淋巴瘤细胞产生的生长调节因子。
Proc Natl Acad Sci U S A. 1986 Dec;83(24):9739-43. doi: 10.1073/pnas.83.24.9739.
10
Natural human interferon-alpha 2 is O-glycosylated.
Biochem J. 1991 Jun 1;276 ( Pt 2)(Pt 2):511-8. doi: 10.1042/bj2760511.

本文引用的文献

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Virus interference. I. The interferon.病毒干扰。一、干扰素。
Proc R Soc Lond B Biol Sci. 1957 Sep 12;147(927):258-67. doi: 10.1098/rspb.1957.0048.
2
Mouse interferons: amino terminal amino acid sequences of various species.小鼠干扰素：不同物种的氨基末端氨基酸序列。
Science. 1980 Feb 1;207(4430):528-30. doi: 10.1126/science.7352261.
3
Amino terminal sequence of the major component of human lymphoblastoid interferon.人淋巴母细胞样干扰素主要成分的氨基末端序列。
Science. 1980 Feb 1;207(4430):527-8. doi: 10.1126/science.7352260.
4
Human fibroblast interferon: amino acid analysis and amino terminal amino acid sequence.人成纤维细胞干扰素：氨基酸分析及氨基末端氨基酸序列
Science. 1980 Feb 1;207(4430):525-6. doi: 10.1126/science.7352259.
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New protein sequenator with increased sensitivity.灵敏度更高的新型蛋白质测序仪。
Science. 1980 Feb 1;207(4430):523-5. doi: 10.1126/science.7352258.
6
Amino acid sequence studies on ten ribosomal proteins of Escherichia coli with an improved sequenator equipped with an automatic conversion device.利用配备自动转换装置的改进型序列分析仪对大肠杆菌的十种核糖体蛋白进行氨基酸序列研究。
Hoppe Seylers Z Physiol Chem. 1973 Oct-Nov;354(10-11):1415-31. doi: 10.1515/bchm2.1973.354.2.1415.
7
Improved manual sequencing methods.改进的手工测序方法。
Methods Enzymol. 1977;47:335-57. doi: 10.1016/0076-6879(77)47036-8.
8
Rapid analysis of amino acid phenylthiohydantoins by high-performance liquid chromatography.通过高效液相色谱法快速分析氨基酸苯硫代乙内酰脲。
Anal Biochem. 1977 Feb;77(2):569-73. doi: 10.1016/0003-2697(77)90276-7.
9
A device coupled to a modified sequenator for the automated conversion of anilinothiazolinones into PTH amino acids.一种与改良测序仪相连的装置，用于将苯胺噻唑啉酮自动转化为PTH氨基酸。
Anal Biochem. 1976 Oct;75(2):621-33. doi: 10.1016/0003-2697(76)90117-2.
10
Human leukocyte interferon purified to homogeneity.纯化至同质的人白细胞干扰素。
Science. 1978 Dec 22;202(4374):1289-90. doi: 10.1126/science.725605.

人白细胞干扰素的氨基末端氨基酸序列

Amino-terminal amino acid sequence of human leukocyte interferon.

作者信息

Levy W P, Shively J, Rubinstein M, Del Valle U, Pestka S

出版信息

Proc Natl Acad Sci U S A. 1980 Sep;77(9):5102-4. doi: 10.1073/pnas.77.9.5102.

DOI:10.1073/pnas.77.9.5102
PMID:6159637
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC350004/
Abstract

We report the amino-terminal sequence of the first 22 amino acids of human leukocyte interferon. These and other results indicate that human leukocyte interferon consists of many individual species. We, therefore, postulate that diversity in this protein is routinely present and that the human leukocyte interferons represent a multigene family.

摘要

我们报道了人白细胞干扰素前22个氨基酸的氨基末端序列。这些结果以及其他结果表明，人白细胞干扰素由许多不同的种类组成。因此，我们推测这种蛋白质中通常存在多样性，并且人白细胞干扰素代表一个多基因家族。