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肠道腺病毒与4型腺病毒之间的交叉反应性:通过固相免疫电子显微镜分析表位

Cross-reactivity between enteric adenoviruses and adenovirus type 4: analysis of epitopes by solid-phase immune electron microscopy.

作者信息

Svensson L, Wadell G, Uhnoo I, Johansson M, Von Bonsdorff C H

出版信息

J Gen Virol. 1983 Nov;64 (Pt 11):2517-20. doi: 10.1099/0022-1317-64-11-2517.

DOI:10.1099/0022-1317-64-11-2517
PMID:6196441
Abstract

The immunological relationships between the two newly discovered serotypes of enteric adenoviruses, Ad40 and Ad41, and antisera to human adenoviruses representing all subgroups were studied by solid-phase immune electron microscopy. A pronounced two-way cross-reaction was seen between Ad40 (subgroup F) and Ad41 (subgroup G). Furthermore, a distinct one-way cross-reaction was noted between adenovirus type 4 antiserum (subgroup E) and virions of Ad40.

摘要

通过固相免疫电子显微镜研究了新发现的两种肠道腺病毒血清型Ad40和Ad41与代表所有亚组的人腺病毒抗血清之间的免疫关系。在Ad40(F亚组)和Ad41(G亚组)之间观察到明显的双向交叉反应。此外,还注意到4型腺病毒抗血清(E亚组)与Ad40病毒粒子之间存在明显的单向交叉反应。

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