关于复发性疱疹疫苗接种效果的动物研究。
Animal studies on the efficacy of vaccination against recurrent herpes.
作者信息
Scriba M
出版信息
Med Microbiol Immunol. 1982;171(1):33-42. doi: 10.1007/BF02122705.
PMID:6289061
Abstract
Guinea pigs, latently infected with herpes simplex virus type 2 (HSV 2), were immunized with an HSV 2 vaccine derived from extracts of infected cells and either formol inactivated or detergent treated. Although such postinfection vaccination could significantly increase the titers of neutralizing antibodies, it had no effect on the course of recurrent herpes in these animals.
摘要
用从感染细胞提取物中获得的、经甲醛灭活或去污剂处理的2型单纯疱疹病毒（HSV 2）疫苗对潜伏感染HSV 2的豚鼠进行免疫接种。尽管这种感染后接种疫苗可显著提高中和抗体滴度，但对这些动物复发性疱疹的病程并无影响。
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