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在一种雪兔布尼亚病毒S互补RNA的5'端存在非病毒异源序列。

Nonviral heterogeneous sequences are present at the 5' ends of one species of snowshoe hare bunyavirus S complementary RNA.

作者信息

Bishop D H, Gay M E, Matsuoko Y

出版信息

Nucleic Acids Res. 1983 Sep 24;11(18):6409-18. doi: 10.1093/nar/11.18.6409.

Abstract

Analyses of the 5' ends of snowshoe hare bunyavirus plus sense S RNA species (including mRNA) recovered from infected cells have revealed two types of termini. These include ends that are essentially exact copies of the 3' end of the viral S RNA and others that are similar, but additionally have 13-14 nucleotide extensions that are heterogeneous in sequence. The former probably represent replicative plus sense RNA species, the latter mRNA species that have host cell derived primer sequences.

摘要

对从受感染细胞中回收的雪兔布尼亚病毒正链S RNA种类(包括mRNA)的5'端进行分析,发现了两种类型的末端。这些末端包括与病毒S RNA 3'端基本精确复制的末端,以及其他类似但另外具有13 - 14个核苷酸延伸的末端,这些延伸在序列上是异质的。前者可能代表复制性正链RNA种类,后者是具有宿主细胞衍生引物序列的mRNA种类。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1bf/326382/7cdfe287180e/nar00363-0260-a.jpg

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