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In vitro activity of ceftriaxone alone and in combination with gentamicin, tobramycin, and amikacin against Pseudomonas aeruginosa.头孢曲松单独及与庆大霉素、妥布霉素和阿米卡星联合应用对铜绿假单胞菌的体外活性。
Antimicrob Agents Chemother. 1983 Aug;24(2):305-6. doi: 10.1128/AAC.24.2.305.
2
In vitro and in vivo synergy between ceftriaxone and aminoglycosides against Pseudomonas aeruginosa.头孢曲松与氨基糖苷类药物对铜绿假单胞菌的体外及体内协同作用。
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Global and effective synergism of amikacin, gentamicin or tobramycin when combined with carbenicillin against Pseudomonas aeruginosa.阿米卡星、庆大霉素或妥布霉素与羧苄西林联合使用时对铜绿假单胞菌具有全面且有效的协同作用。
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[Comparison of bactericidal effects of four aminoglycoside antibiotics: amikacin, gentamicin, kanamycin and tobramycin (author's transl)].四种氨基糖苷类抗生素（阿米卡星、庆大霉素、卡那霉素和妥布霉素）杀菌效果的比较（作者译）
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Aminoglycosides plus beta-lactams against gram-negative organisms. Evaluation of in vitro synergy and chemical interactions.氨基糖苷类药物与β-内酰胺类药物联合用于抗革兰氏阴性菌。体外协同作用及化学相互作用的评估。
Am J Med. 1986 Jun 30;80(6B):126-37. doi: 10.1016/0002-9343(86)90490-0.

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Association between antimicrobial drug class selection for treatment and retreatment of bovine respiratory disease and health, performance, and carcass quality outcomes in feedlot cattle.用于治疗和再治疗牛呼吸道疾病的抗菌药物类别选择与肥育牛的健康、性能和胴体质量结果之间的关联。
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Synergistic activities of combinations of beta-lactams, fosfomycin, and tobramycin against Pseudomonas aeruginosa.β-内酰胺类、磷霉素和妥布霉素联合使用对铜绿假单胞菌的协同活性。
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Ceftriaxone. A review of its antibacterial activity, pharmacological properties and therapeutic use.头孢曲松。对其抗菌活性、药理特性及治疗用途的综述。
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5
Comparative synergistic activity of ceftriaxone-piperacillin versus ceftriaxone-netilmicin.头孢曲松-哌拉西林与头孢曲松-奈替米星的比较协同活性
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6
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本文引用的文献

1
Method of reliable determination of minimal lethal antibiotic concentrations.可靠测定最低致死抗生素浓度的方法。
Antimicrob Agents Chemother. 1980 Nov;18(5):699-708. doi: 10.1128/AAC.18.5.699.
2
Antibacterial activity of ceftriaxone (Ro 13-9904), a beta-lactamase-stable cephalosporin.头孢曲松（Ro 13 - 9904）的抗菌活性，一种对β-内酰胺酶稳定的头孢菌素。
Antimicrob Agents Chemother. 1981 Mar;19(3):414-23. doi: 10.1128/AAC.19.3.414.
3
Comparative in vitro activities of beta-lactam-tobramycin combinations against Pseudomonas aeruginosa and multidrug-resistant gram-negative enteric bacilli.β-内酰胺类与妥布霉素联合用药对铜绿假单胞菌和多重耐药革兰氏阴性肠道杆菌的体外比较活性
Antimicrob Agents Chemother. 1982 Jun;21(6):1003-6. doi: 10.1128/AAC.21.6.1003.
4
Comparative in vitro studies of Ro 13-9904, a new cephalosporin derivative.新型头孢菌素衍生物Ro 13-9904的体外比较研究
Antimicrob Agents Chemother. 1981 Mar;19(3):435-42. doi: 10.1128/AAC.19.3.435.
5
Bactericidal and synergistic activity of moxalactam alone and in combination with gentamicin against Pseudomonas aeruginosa.羟羧氧酰胺菌素单独及与庆大霉素联合对铜绿假单胞菌的杀菌及协同活性。
Antimicrob Agents Chemother. 1983 Jan;23(1):179-81. doi: 10.1128/AAC.23.1.179.

头孢曲松单独及与庆大霉素、妥布霉素和阿米卡星联合应用对铜绿假单胞菌的体外活性。

In vitro activity of ceftriaxone alone and in combination with gentamicin, tobramycin, and amikacin against Pseudomonas aeruginosa.

作者信息

Watanakunakorn C

出版信息

Antimicrob Agents Chemother. 1983 Aug;24(2):305-6. doi: 10.1128/AAC.24.2.305.

DOI:10.1128/AAC.24.2.305
PMID:6314890
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC185160/
Abstract

The in vitro activity of ceftriaxone alone and in combination with gentamicin, tobramycin, and amikacin against 50 Pseudomonas aeruginosa strains was studied by the broth dilution method and the time-kill curve method. The majority of the P. aeruginosa strains tested were resistant to ceftriaxone. Combining ceftriaxone with the aminoglycosides resulted in synergism, antagonism, or indifference.

摘要

采用肉汤稀释法和时间杀菌曲线法，研究了头孢曲松单独以及与庆大霉素、妥布霉素和阿米卡星联合使用时对50株铜绿假单胞菌的体外活性。大多数受试铜绿假单胞菌菌株对头孢曲松耐药。头孢曲松与氨基糖苷类药物联合使用可产生协同、拮抗或无相互作用的结果。