头孢曲松单独及与庆大霉素、妥布霉素和阿米卡星联合应用对铜绿假单胞菌的体外活性。
In vitro activity of ceftriaxone alone and in combination with gentamicin, tobramycin, and amikacin against Pseudomonas aeruginosa.
作者信息
Watanakunakorn C
出版信息
Antimicrob Agents Chemother. 1983 Aug;24(2):305-6. doi: 10.1128/AAC.24.2.305.
Abstract
The in vitro activity of ceftriaxone alone and in combination with gentamicin, tobramycin, and amikacin against 50 Pseudomonas aeruginosa strains was studied by the broth dilution method and the time-kill curve method. The majority of the P. aeruginosa strains tested were resistant to ceftriaxone. Combining ceftriaxone with the aminoglycosides resulted in synergism, antagonism, or indifference.
摘要
采用肉汤稀释法和时间杀菌曲线法，研究了头孢曲松单独以及与庆大霉素、妥布霉素和阿米卡星联合使用时对50株铜绿假单胞菌的体外活性。大多数受试铜绿假单胞菌菌株对头孢曲松耐药。头孢曲松与氨基糖苷类药物联合使用可产生协同、拮抗或无相互作用的结果。
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