白三烯B4，一种存在于类风湿性关节炎滑液中的炎症介质。
Leukotriene B4, a mediator of inflammation present in synovial fluid in rheumatoid arthritis.
作者信息
Davidson E M, Rae S A, Smith M J
出版信息
Ann Rheum Dis. 1983 Dec;42(6):677-9. doi: 10.1136/ard.42.6.677.
Abstract
Leukotriene B4 (LTB4), generated from arachidonic acid following lipoxygenase activity by a variety of inflammatory leucocytes, has been shown to be present in synovial fluid from patients with active rheumatoid arthritis. It does not persist as such, being converted to less active metabolites. The role of LTB4 as one of the natural mediators of inflammation is discussed.
摘要
白三烯B4（LTB4）由多种炎性白细胞通过脂氧合酶活性作用于花生四烯酸产生，已证实在类风湿关节炎活动期患者的滑液中存在。它不会以这种形式持续存在，而是会转化为活性较低的代谢产物。本文讨论了LTB4作为炎症天然介质之一的作用。
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本文引用的文献
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Identification and biological activity of novel omega-oxidized metabolites of leukotriene B4 from human leukocytes.人白细胞中白三烯B4新型ω-氧化代谢产物的鉴定及其生物学活性
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Leukotriene B4: an inflammatory mediator in vivo.白三烯B4：一种体内炎症介质。
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Rapid extraction of oxygenated metabolites of arachidonic acid from biological samples using octadecylsilyl silica.使用十八烷基硅烷硅胶从生物样品中快速提取花生四烯酸的氧化代谢物。
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