Jones M D, Foster L, Sheedy T, Griffin B E
EMBO J. 1984 Apr;3(4):813-21. doi: 10.1002/j.1460-2075.1984.tb01890.x.
Epstein-Barr virus (EBV) DNA isolated from the frequently studied and unusual Burkitt's lymphoma cell line, Daudi, contains a 7.4-kb deletion, similar to (but larger than) that found in a non-transforming isolate of the virus, P3HR-1. A comparison of EBV sequence in Daudi cells with that from a comparable region in a wild-type, transforming strain of the virus (B95-8) indicates that at least two of the previously identified RNAs, a highly repetitive sequence, and other interesting coding or structural features should be absent in Daudi EBV DNA as a consequence of the deletion. The information removed by the deletion, as well as that which might be generated by juxtaposition of two regions of the genome that are not adjacent in most strains of the virus are discussed.
从经常被研究的、不同寻常的伯基特淋巴瘤细胞系Daudi中分离出的爱泼斯坦-巴尔病毒（EBV）DNA含有一个7.4kb的缺失，这与在该病毒的一个非转化分离株P3HR-1中发现的缺失相似（但更大）。将Daudi细胞中的EBV序列与病毒野生型转化株（B95-8）中可比区域的序列进行比较表明，由于该缺失，Daudi EBV DNA中至少两个先前鉴定的RNA、一个高度重复序列以及其他有趣的编码或结构特征应该不存在。讨论了因缺失而去除的信息，以及可能由病毒大多数菌株中不相邻的基因组两个区域并列产生的信息。
