使用与牛血清白蛋白偶联的分离荚膜抗原预防大鼠由大肠杆菌引起的急性上行性肾盂肾炎。
Protection against acute, ascending pyelonephritis caused by Escherichia coli in rats, using isolated capsular antigen conjugated to bovine serum albumin.
作者信息
Kaijser B, Larsson P, Olling S, Schneerson R
出版信息
Infect Immun. 1983 Jan;39(1):142-6. doi: 10.1128/iai.39.1.142-146.1983.
Abstract
We found that isolated Escherichia coli K13 antigen conjugated to bovine serum albumin, in contrast to isolated, non-conjugated K13, was highly immunogenic and induced protection against acute pyelonephritis caused by E. coli O6K13H1 in rats.
摘要
我们发现，与分离出的未结合的K13抗原相比，与牛血清白蛋白结合的分离出的大肠杆菌K13抗原具有高度免疫原性，并能诱导大鼠抵抗由大肠杆菌O6K13H1引起的急性肾盂肾炎。
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