Le Bras J, Deloron P
Am J Trop Med Hyg. 1983 May;32(3):447-51. doi: 10.4269/ajtmh.1983.32.447.
A modification of Rieckmann's microtechnique was used to determine the drug sensitivity of Plasmodium falciparum. The technique was found to be reliable and adequately sensitive with either blood from a malarial patient or strains of P. falciparum from in vitro continuous culture, with a success rate of 50%. Minor variations in the method had little influence on the results. Inhibition of maturation of parasites was compared with the inhibition of increase in parasitemia.
采用里克曼微技术的一种改良方法来测定恶性疟原虫的药物敏感性。结果发现，该技术对于疟疾患者的血液或体外连续培养的恶性疟原虫菌株而言，都是可靠且具有足够敏感性的，成功率为50%。该方法的微小变化对结果影响不大。将寄生虫成熟的抑制情况与疟原虫血症增加的抑制情况进行了比较。
