嗜肺军团菌在口咽部的定植。
Oropharyngeal colonization with Legionella pneumophila.
作者信息
Bridge J A, Edelstein P H
出版信息
J Clin Microbiol. 1983 Nov;18(5):1108-12. doi: 10.1128/jcm.18.5.1108-1112.1983.
Abstract
A total of 186 volunteers, including 40 hospital patients, participated in a cross-sectional survey of oropharyngeal colonization with Legionella pneumophila. Colonization was defined as the appearance of any L. pneumophila organisms on culture or a positive direct fluorescent-antibody (FA) test or both in the absence of signs or symptoms of pneumonia. The direct FA tests were performed on throat swabs, using a polyvalent conjugate directed against L. pneumophila serogroups I through IV. Throat swabs were cultured for L. pneumophila on a selective medium. Blood specimens were tested for antibody, using an indirect FA test and heat-killed polyvalent antigen for L. pneumophila serogroups I through IV. Eight people, none of whom had pneumonia or fever, had positive direct FA tests; no subject had a positive culture for L. pneumophila. Whether the positive direct FA results represent colonization cannot be stated with assurance. In any case, the results suggest that colonization occurs infrequently.
摘要
共有186名志愿者，包括40名住院患者，参与了一项关于嗜肺军团菌口咽定植的横断面调查。定植定义为在没有肺炎体征或症状的情况下，培养物中出现任何嗜肺军团菌生物体，或直接荧光抗体（FA）检测呈阳性，或两者均呈阳性。使用针对嗜肺军团菌血清群I至IV的多价结合物对咽拭子进行直接FA检测。咽拭子在选择性培养基上培养嗜肺军团菌。使用间接FA检测和针对嗜肺军团菌血清群I至IV的热灭活多价抗原对血液标本进行抗体检测。8人直接FA检测呈阳性，其中无人患有肺炎或发热；没有受试者嗜肺军团菌培养呈阳性。无法确定直接FA检测阳性结果是否代表定植。无论如何，结果表明定植很少发生。
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