Numazaki K, Chiba S, Nakata S, Yamanaka T, Nakao T
Pediatr Infect Dis. 1984 Mar-Apr;3(2):105-9. doi: 10.1097/00006454-198403000-00004.
The incidence of humoral antibodies to Chlamydia trachomatis was determined in 1005 Japanese individuals of various ages. Formalin-fixed purified reticulate bodies of C. trachomatis (L2(434) strain) were used as antigens in the microimmunofluorescence test. Of 137 pregnant women, 25 (18.2%) had antibody titers of 1:10 or larger. Of 120 cord blood specimens from newborns, 16 (13.3%) were positive. Among 565 infants and children a progressive, age-related increase in seropositivity was observed except in 6- to 8-year-olds: 9.2% for infants under 1 year old; 20.8 to 25.0% for 1-to 5-year-olds; 11.7 to 17.6% for 6- to 8-year-olds; and 26.1 to 32.3% for 9- to 15-year-olds. Among 183 adults the seropositivity rate was between 20.0 and 26.7%, and a progressive increase in seropositivity was not clearly observed. These data suggest that C. trachomatis infection occurs commonly in Japanese adults and children.
在1005名不同年龄段的日本人中测定了沙眼衣原体体液抗体的发生率。在微量免疫荧光试验中，使用福尔马林固定的沙眼衣原体（L2(434)菌株）纯化网状体作为抗原。137名孕妇中，25名（18.2%）抗体滴度为1:10或更高。在120份新生儿脐带血标本中，16份（13.3%）呈阳性。在565名婴幼儿中，除6至8岁儿童外，血清阳性率随年龄增长呈上升趋势：1岁以下婴儿为9.2%；1至5岁儿童为20.8%至25.0%；6至8岁儿童为11.7%至17.6%；9至15岁儿童为26.1%至32.3%。183名成年人中，血清阳性率在20.0%至26.7%之间，未观察到血清阳性率的逐渐上升。这些数据表明，沙眼衣原体感染在日本成年人和儿童中普遍存在。
