人体肠道黏膜中缺乏K细胞。
Absence of K cells in human gut mucosa.
作者信息
Clancy R, Pucci A
出版信息
Gut. 1978 Apr;19(4):273-6. doi: 10.1136/gut.19.4.273.
Abstract
Lymphocytes have been isolated from human rectal biopsies in numbers sufficient for microassay procedures. No antibody-dependent cell-mediated cytotoxic (ADCC) activity could be detected in normal or inflamed human gut mucosa, using two assay systems which detect predominantly K cell activity. The tissue localisation and circulation characteristics of K cells require definition before establishing their role as an efferent immunological mechanism.
摘要
已从人直肠活检组织中分离出数量足以用于微量测定程序的淋巴细胞。使用两种主要检测K细胞活性的测定系统，在正常或发炎的人肠道黏膜中均未检测到抗体依赖性细胞介导的细胞毒性（ADCC）活性。在确定K细胞作为传出免疫机制的作用之前，需要明确其组织定位和循环特征。
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