依诺沙星及其他17种抗菌剂对多重耐药革兰氏阴性菌的体外活性
In vitro activities of enoxacin and 17 other antimicrobial agents against multiply resistant, gram-negative bacteria.
作者信息
Rudrik J T, Cavalieri S J, Britt E M
出版信息
Antimicrob Agents Chemother. 1984 Jul;26(1):97-100. doi: 10.1128/AAC.26.1.97.
Abstract
Enoxacin (CI-919) was evaluated for activity against 120 multiply resistant clinical isolates of the family Enterobacteriaceae and Pseudomonas aeruginosa. The MIC of enoxacin for 95% of the strains tested was less than or equal to 2 micrograms/ml. Approximately 90% of the isolates were susceptible to enoxacin, norfloxacin, ceftazidime, moxalactam, cefotaxime, cefoperazone, and amikacin. Marked resistance to the other seven antimicrobial agents tested was observed.
摘要
对依诺沙星（CI - 919）针对120株多重耐药的肠杆菌科细菌和铜绿假单胞菌临床分离株的活性进行了评估。依诺沙星对95%受试菌株的最低抑菌浓度小于或等于2微克/毫升。约90%的分离株对依诺沙星、诺氟沙星、头孢他啶、拉氧头孢、头孢噻肟、头孢哌酮和阿米卡星敏感。观察到对所测试的其他七种抗菌药物有明显耐药性。
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