McNabb W R, Shanson D C, Williams T D, Lant A F
J R Soc Med. 1984 Jul;77(7):550-5. doi: 10.1177/014107688407700705.
Strep. pneumoniae was diagnosed as the cause of pneumonia in 40 (50%) of 80 consecutive adults admitted to St Stephen's Hospital with community-acquired pneumonia. None of the patients had evidence of Mycoplasma pneumoniae infection, and Legionella pneumophila serology was positive on only one occasion. In 29 patients (36%) no causative organism was demonstrated. The diagnosis of pneumococcal infection was obtained in 15 cases by isolating Strep. pneumoniae from the sputum, in 13 further cases by demonstrating pneumococcal capsular antigen in sputum, and in 12 other cases by detecting pneumococcal antigen in serum only. Only 2 cases with pneumococcal pneumonia were bacteraemic and 3 patients (7%), all aged more than 75 years, died. The relatively low bacteraemic and mortality rates suggest that community-acquired pneumococcal pneumonia currently seen in patients admitted to hospital in central London may not be so severe as in some other areas.
在连续入住圣斯蒂芬医院的80名社区获得性肺炎成年患者中，40例（50%）被诊断为肺炎链球菌所致肺炎。所有患者均无肺炎支原体感染证据，嗜肺军团菌血清学检查仅1例呈阳性。29例（36%）患者未发现致病病原体。15例通过从痰液中分离出肺炎链球菌确诊为肺炎球菌感染，另有13例通过检测痰液中的肺炎球菌荚膜抗原确诊，还有12例仅通过检测血清中的肺炎球菌抗原确诊。仅2例肺炎球菌肺炎患者发生菌血症，3例患者（7%）死亡，均为75岁以上老人。菌血症和死亡率相对较低，表明目前在伦敦市中心住院患者中所见的社区获得性肺炎球菌肺炎可能不像其他一些地区那样严重。
