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铍淋巴细胞转化试验在慢性铍病及潜在暴露工人中的价值。

Value of beryllium lymphocyte transformation tests in chronic beryllium disease and in potentially exposed workers.

作者信息

Williams W J, Williams W R

出版信息

Thorax. 1983 Jan;38(1):41-4. doi: 10.1136/thx.38.1.41.

Abstract

The beryllium lymphocyte transformation test was performed on 16 patients with chronic beryllium disease, 10 subjects (seven patients and three young boys) who were under suspicion, and 117 healthy beryllium workers. The tests gave a positive response in all patients with definite disease and a negative response in the suspected group. Two of the healthy workers had a positive response, indicating both exposure and sensitisation. It is not known whether sensitised workers are more liable to develop disease. We consider that the test is of value in the diagnosis of beryllium disease and advocate its use in monitoring the health of potentially exposed workers.

摘要

对16例慢性铍病患者、10名疑似患者(7名患者和3名小男孩)以及117名健康铍作业工人进行了铍淋巴细胞转化试验。所有确诊患者的试验结果均为阳性,疑似组的试验结果为阴性。117名健康工人中有2人试验结果呈阳性,表明他们既接触过铍且已致敏。尚不清楚已致敏的工人是否更易患铍病。我们认为该试验对铍病的诊断有价值,并提倡用其监测可能接触铍的工人的健康状况。

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本文引用的文献

1
Berylliosis: a case report.铍中毒:一例病例报告。
Br Med J. 1955 Jun 18;1(4928):1448-50. doi: 10.1136/bmj.1.4928.1448.
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Beryllium disease: a clinical perspective.铍病:临床视角
Environ Res. 1980 Feb;21(1):1-9. doi: 10.1016/0013-9351(80)90002-x.
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In vitro studies on granulomatous hypersensitivity to beryllium.
J Invest Dermatol. 1970 Oct;55(4):284-8. doi: 10.1111/1523-1747.ep12260036.
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Diagnosis of chronic beryllium disease.慢性铍病的诊断
Br Med J. 1972 Oct 21;4(5833):175. doi: 10.1136/bmj.4.5833.175-b.

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