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酵母中负责组成型酸性磷酸酶合成的着丝粒连锁基因的定位

Mapping of a centromere-linked gene responsible for constitutive acid phosphatase synthesis in yeast.

作者信息

Lange P, Hansche P E

出版信息

Mol Gen Genet. 1980;180(3):605-7. doi: 10.1007/BF00268067.

DOI:10.1007/BF00268067
PMID:7007824
Abstract

From a chemostat in which the activity of acid phosphatase was limiting, a mutant with a constitutive acid phosphatase was selected. This gene (pho80) responsible for the production of a repressor was mapped 5.3 centimorgans apart from the centromere on the right arm of chromosome XV.

摘要

从一个酸性磷酸酶活性受限的恒化器中，筛选出了一个具有组成型酸性磷酸酶的突变体。负责产生阻遏物的这个基因（pho80）被定位在第十五号染色体右臂上，距离着丝粒5.3厘摩处。

相似文献

1
Mapping of a centromere-linked gene responsible for constitutive acid phosphatase synthesis in yeast.酵母中负责组成型酸性磷酸酶合成的着丝粒连锁基因的定位
Mol Gen Genet. 1980;180(3):605-7. doi: 10.1007/BF00268067.
2
Mutations in the pho80 gene confer permeability to 5'-mononucleotides in Saccharomyces cerevisiae.酵母中pho80基因的突变赋予了对5'-单核苷酸的通透性。
Genetics. 1982 Nov;102(3):341-59. doi: 10.1093/genetics/102.3.341.
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Structure and function of the PHO82-pho4 locus controlling the synthesis of repressible acid phosphatase of Saccharomyces cerevisiae.控制酿酒酵母可阻遏酸性磷酸酶合成的PHO82-pho4基因座的结构与功能
J Bacteriol. 1981 Jan;145(1):221-32. doi: 10.1128/jb.145.1.221-232.1981.
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The PHO80/TUP7 locus in Saccharomyces cerevisiae is on the left arm of chromosome XV: mapping by chromosome engineering.酿酒酵母中的PHO80/TUP7基因座位于第十五号染色体的左臂：通过染色体工程进行定位。
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[Genetico-biochemical study of the acid phosphatases of Saccharomyces cerevisiae yeasts. X. Analysis of mutations arising in gene acp3].[酿酒酵母酸性磷酸酶的遗传生化研究。X. acp3基因中产生的突变分析]
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Negative regulatory elements of the Saccharomyces cerevisiae PHO system: interaction between PHO80 and PHO85 proteins.酿酒酵母PHO系统的负调控元件：PHO80与PHO85蛋白之间的相互作用
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Structure and expression of the PHO80 gene of Saccharomyces cerevisiae.酿酒酵母PHO80基因的结构与表达
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Cloning and sequencing of the PHO80 gene and CEN15 of Saccharomyces cerevisiae.酿酒酵母PHO80基因和CEN15的克隆与测序。
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Genetic mapping of 1,3-beta-glucanase-encoding genes in Saccharomyces cerevisiae.酿酒酵母中1,3-β-葡聚糖酶编码基因的遗传定位
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Isolation of the centromere-linked CDC10 gene by complementation in yeast.通过酵母互补作用分离着丝粒连接的CDC10基因。
Proc Natl Acad Sci U S A. 1980 Apr;77(4):2173-7. doi: 10.1073/pnas.77.4.2173.

引用本文的文献

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Acid phosphatases of budding yeast as a model of choice for transcription regulation research.出芽酵母的酸性磷酸酶作为转录调控研究的首选模型。
Enzyme Res. 2011;2011:356093. doi: 10.4061/2011/356093. Epub 2011 Jul 10.
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Two yeast acid phosphatase structural genes are the result of a tandem duplication and show different degrees of homology in their promoter and coding sequences.两个酵母酸性磷酸酶结构基因是串联重复的结果，并且在其启动子和编码序列中显示出不同程度的同源性。
EMBO J. 1982;1(6):675-80. doi: 10.1002/j.1460-2075.1982.tb01229.x.
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Regulated expression of a human interferon gene in yeast: control by phosphate concentration or temperature.

本文引用的文献

1
Genetic mapping of nonsense suppressors in yeast.酵母中无义抑制基因的遗传图谱
Genetics. 1968 Dec;60(4):735-42. doi: 10.1093/genetics/60.4.735.
2
Directed evolution of metabolic pathways in microbial populations. I. Modification of the acid phosphatase pH optimum in S. cerevisiae.微生物群体中代谢途径的定向进化。I. 酿酒酵母中酸性磷酸酶最适pH的修饰。
Genetics. 1972 Jan;70(1):59-73. doi: 10.1093/genetics/70.1.59.
3
Isolation and characterization of recessive, constitutive mutations for repressible acid phosphatase synthesis in Saccharomyces cerevisiae.
人干扰素基因在酵母中的调控表达：受磷酸盐浓度或温度的控制。
Proc Natl Acad Sci U S A. 1984 Jan;81(2):367-70. doi: 10.1073/pnas.81.2.367.
4
Selection in chemostats.恒化器中的选择
Microbiol Rev. 1983 Jun;47(2):150-68. doi: 10.1128/mr.47.2.150-168.1983.
5
Regulation of repressible acid phosphatase gene transcription in Saccharomyces cerevisiae.酿酒酵母中可阻遏酸性磷酸酶基因转录的调控
Mol Cell Biol. 1985 Aug;5(8):2131-41. doi: 10.1128/mcb.5.8.2131-2141.1985.
酿酒酵母中可阻遏酸性磷酸酶合成的隐性组成型突变的分离与鉴定。
J Bacteriol. 1975 Jun;122(3):911-22. doi: 10.1128/jb.122.3.911-922.1975.
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Gene duplication in Saccharomyces cerevisiae.酿酒酵母中的基因复制。
Genetics. 1978 Apr;88(4 Pt 1):673-87.
5
Localization of acid phosphatase in Saccharomyces cerevisiae: a clue to cell wall formation.酿酒酵母中酸性磷酸酶的定位：细胞壁形成的线索
J Bacteriol. 1977 Aug;131(2):638-44. doi: 10.1128/jb.131.2.638-644.1977.
6
Gene duplication as a mechanism of genetic adaptation in Saccharomyces cerevisiae.基因复制作为酿酒酵母遗传适应的一种机制。
Genetics. 1975 Apr;79(4):661-74. doi: 10.1093/genetics/79.4.661.
7
Ultracytochemical characterization of non-specific acid phosphatase activities in Saccharomyces cerevisiae.酿酒酵母中非特异性酸性磷酸酶活性的超微细胞化学表征
Z Allg Mikrobiol. 1979;19(7):455-65. doi: 10.1002/jobm.3630190702.