Wong V C, Lee A K, Ip H M
Br J Obstet Gynaecol. 1980 Nov;87(11):958-65. doi: 10.1111/j.1471-0528.1980.tb04458.x.
Materno-fetal transmission of hepatitis B was studied in 97 healthy carriers of hepatitis B surface antigen (HBsAg). Antepartum transmission occurred in at least 10 per cent. Intrapartum transmission may have occurred in about 40 per cent as a result of swallowing of the infective fluid by the baby during delivery, and materno-fetal transfusion during labour. Person to person transmission after delivery played a minor role. The presence of hepatitis B associated e antigen (HBeAg) in 48 per cent of maternal serum correlated strongly with the subsequent presence of antigen in the infants. There was a linear association between the incidence of antigens in cord blood and the duration of the first stage of labour, with a significant association when labour exceeded nine hours. Caesarean section is recommended if mothers have HbeAg; likewise amniocentesis and breast feeding should be discouraged if mothers have HbeAg.
对97名健康的乙型肝炎表面抗原（HBsAg）携带者进行了母婴传播乙型肝炎的研究。产前传播发生率至少为10%。分娩时传播可能约占40%，这是由于婴儿在分娩过程中吞咽了感染性液体以及分娩时发生了母婴输血。产后人与人之间的传播作用较小。48%的母体血清中存在乙型肝炎e抗原（HBeAg）与婴儿随后出现该抗原密切相关。脐血中抗原的发生率与第一产程的持续时间呈线性关系，当产程超过9小时时有显著相关性。如果母亲有HbeAg，建议进行剖宫产；同样，如果母亲有HbeAg，应不鼓励进行羊膜穿刺术和母乳喂养。
