Goodman H M, Ecker J R, Dean C
Department of Genetics, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA.
Proc Natl Acad Sci U S A. 1995 Nov 21;92(24):10831-5. doi: 10.1073/pnas.92.24.10831.
Arabidopsis thaliana is a small flowering plant that is a member of the family cruciferae. It has many characteristics--diploid genetics, rapid growth cycle, relatively low repetitive DNA content, and small genome size--that recommend it as the model for a plant genome project. The current status of the genetic and physical maps, as well as efforts to sequence the genome, are presented. Examples are given of genes isolated by using map-based cloning. The importance of the Arabidopsis project for plant biology in general is discussed.
拟南芥是一种小型开花植物，属于十字花科。它具有许多特性——二倍体遗传学、快速生长周期、相对较低的重复DNA含量以及小基因组大小——这些特性使其成为植物基因组计划的模式植物。本文介绍了遗传图谱和物理图谱的现状，以及基因组测序的工作进展。文中给出了通过图位克隆分离基因的实例。讨论了拟南芥计划对整个植物生物学的重要性。
