质粒pSa的aadA2基因的修订分析
Revised analysis of aadA2 gene of plasmid pSa.
作者信息
Bito A, Susani M
机构信息
Institut für Genetik und Allgemeine Biologie, Universität Salzburg, Austria.
出版信息
Antimicrob Agents Chemother. 1994 May;38(5):1172-5. doi: 10.1128/AAC.38.5.1172.
Abstract
The nucleotide sequence of gene aadA2 of plasmid pSa, coding for aminoglycoside-3"-adenyltransferase, has been reexamined. We found differences with respect to the sequence previously determined by Tait et al. (R. C. Tait, H. Rempel, R. L. Rodriguez, and C. I. Kado, Gene 36:97-104, 1985). These deviations are located in the coding region and in the 3' noncoding region. By making deletions in the region for initiation of protein synthesis, we identified a GTG triplet as the most probable start codon for translation.
摘要
编码氨基糖苷-3''-腺苷转移酶的质粒pSa的aadA2基因的核苷酸序列已被重新检测。我们发现与泰特等人（R.C.泰特、H.雷empel、R.L.罗德里格斯和C.I.卡多，《基因》36:97 - 104，1985年）先前确定的序列存在差异。这些偏差位于编码区和3'非编码区。通过在蛋白质合成起始区域进行缺失操作，我们确定GTG三联体是最可能的翻译起始密码子。
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本文引用的文献
1
Site-specific insertion of gene cassettes into integrons.基因盒在整合子中的位点特异性插入。
Mol Microbiol. 1993 Jul;9(1):41-52. doi: 10.1111/j.1365-2958.1993.tb01667.x.
2
Characterization of translational initiation sites in E. coli.大肠杆菌中转录起始位点的表征
Nucleic Acids Res. 1982 May 11;10(9):2971-96. doi: 10.1093/nar/10.9.2971.
3
Broad-host-range cloning vectors derived from the W-plasmid Sa.源自W质粒Sa的广宿主范围克隆载体。
Gene. 1982 Oct;19(3):361-4. doi: 10.1016/0378-1119(82)90027-0.
4
Formation of an RNA primer for initiation of replication of ColE1 DNA by ribonuclease H.核糖核酸酶H形成用于启动ColE1 DNA复制的RNA引物。
Proc Natl Acad Sci U S A. 1980 May;77(5):2450-4. doi: 10.1073/pnas.77.5.2450.
5
The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites.大肠杆菌16S核糖体RNA的3'末端序列：与无义三联体及核糖体结合位点的互补性
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1342-6. doi: 10.1073/pnas.71.4.1342.
6
Characterization of transferable plasmids from Shigella flexneri 2a that confer resistance to trimethoprim, streptomycin, and sulfonamides.福氏志贺菌2a中赋予对甲氧苄啶、链霉素和磺胺类药物耐药性的可转移质粒的特性分析。
Plasmid. 1986 Mar;15(2):119-31. doi: 10.1016/0147-619x(86)90048-x.
7
DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.使用改良的噬菌体T7 DNA聚合酶进行DNA序列分析。
Proc Natl Acad Sci U S A. 1987 Jul;84(14):4767-71. doi: 10.1073/pnas.84.14.4767.
8
Plasmid vector pBR322 and its special-purpose derivatives--a review.质粒载体pBR322及其专用衍生物——综述
Gene. 1986;50(1-3):3-40. doi: 10.1016/0378-1119(86)90307-0.
9
The aminoglycoside-resistance operon of the plasmid pSa: nucleotide sequence of the streptomycin-spectinomycin resistance gene.质粒pSa的氨基糖苷抗性操纵子：链霉素-壮观霉素抗性基因的核苷酸序列
Gene. 1985;36(1-2):97-104. doi: 10.1016/0378-1119(85)90073-3.
10
Nucleotide sequence of the transposon Tn7 gene encoding an aminoglycoside-modifying enzyme, 3"(9)-O-nucleotidyltransferase.编码氨基糖苷修饰酶3"(9)-O-核苷酸转移酶的转座子Tn7基因的核苷酸序列。
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