Manivannan A, Kirkpatrick J N, Sharp P F, Forrester J V
Department of BioMedical Physics and BioEngineering, University of Aberdeen, Scotland.
Br J Ophthalmol. 1994 Feb;78(2):84-90. doi: 10.1136/bjo.78.2.84.
An infrared scanning laser ophthalmoscope (SLO) has been custom built in order to investigate the application of confocal and indirect mode SLO imaging to patients with fundus disease. Infrared light is reflected from the fundus to a greater extent than visible light permitting lower illumination power and, as it penetrates the retinal pigment epithelium, choroidal structures can be readily imaged. Furthermore, as conventional infrared illumination and detection systems are not well suited to ophthalmoscopy, this area is underdeveloped as a potential source of useful clinical data. Confocal, direct and indirect imaging modes have been used to image fundi of normal volunteers and patients with fundus disease. In comparison with conventional fundus photography confocal infrared SLO imaging improves visualisation of choroidal vasculature, retinal pigment epithelial abnormalities, laser photocoagulation scars, and optic disc pores in the lamina cribrosa. Direct infrared SLO imaging enables fundus visualisation through nuclear lens opacities. Furthermore, indirect mode imaging enhances significantly the appearance of macular drusen. The potential clinical benefit of these observations is discussed.
为了研究共聚焦和间接模式扫描激光检眼镜（SLO）成像在眼底疾病患者中的应用，我们特制了一台红外扫描激光检眼镜。红外光从眼底反射的程度比可见光更大，这使得照明功率更低，并且由于它能穿透视网膜色素上皮，脉络膜结构能够很容易地成像。此外，由于传统的红外照明和检测系统不太适合检眼镜检查，作为有用临床数据的潜在来源，这一领域尚未得到充分发展。共聚焦、直接和间接成像模式已被用于对正常志愿者和眼底疾病患者的眼底进行成像。与传统眼底摄影相比，共聚焦红外SLO成像改善了脉络膜血管系统、视网膜色素上皮异常、激光光凝瘢痕以及筛板层视盘孔的可视化。直接红外SLO成像能够透过核性晶状体混浊实现眼底可视化。此外，间接模式成像显著增强了黄斑玻璃膜疣的外观。我们还讨论了这些观察结果潜在的临床益处。
