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肝癌经导管动脉栓塞治疗后肝脏实质改变:CT评估

Liver parenchymal changes after transcatheter arterial embolization therapy for hepatoma: CT evaluation.

作者信息

Yamashita Y, Torashima M, Oguni T, Yamamoto A, Harada M, Miyazaki T, Takahashi M

机构信息

Department of Radiology, Kumamoto University School of Medicine, Japan.

出版信息

Abdom Imaging. 1993 Fall;18(4):352-6. doi: 10.1007/BF00201780.

DOI:10.1007/BF00201780
PMID:8220035
Abstract

We retrospectively reviewed computed tomographic (CT) findings of 118 patients with hepatoma who received sequential follow-up CT after transcatheter arterial embolization (TAE). Thirty-five patients received TAE using Gelfoam particles with cisplatin, 37 patients using Gelfoam particles and iodized oil (Lipiodol) with cisplatin, and 46 patients using iodized oil with cisplatin. Liver atrophy was observed in 33 patients, lobarly or focally, depending on the embolized area. It was frequently associated with portal vein occlusion by the tumor, usage of iodized oil, and repeated embolization therapy. The lobar atrophy was seen in patients who had portal vein occlusion and/or received repeated embolization therapy. The focal atrophy was observed in patients who were administered iodized oil. Infarction developed in four patients who had a thrombus in the portal vein and received peripheral embolization therapy using iodized oil. We conclude that liver parenchymal changes occur frequently in patients who have portal vein occlusion and/or receive peripheral embolization using iodized oil.

摘要

我们回顾性分析了118例肝癌患者经肝动脉化疗栓塞术(TAE)后接受序贯CT随访的CT表现。35例患者使用明胶海绵颗粒加顺铂进行TAE,37例患者使用明胶海绵颗粒加碘化油(碘油)加顺铂,46例患者使用碘化油加顺铂。33例患者出现肝脏萎缩,呈叶性或局灶性,取决于栓塞区域。其常与肿瘤导致的门静脉闭塞、碘化油的使用以及重复栓塞治疗有关。叶性萎缩见于门静脉闭塞和/或接受重复栓塞治疗的患者。局灶性萎缩见于使用碘化油的患者。4例门静脉有血栓且接受碘化油外周栓塞治疗的患者发生了梗死。我们得出结论,门静脉闭塞和/或使用碘化油进行外周栓塞的患者肝脏实质改变频繁发生。

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