评估一种在全科医疗中减少苯二氮䓬类药物使用的简便且具成本效益的策略。
Evaluation of an easy, cost-effective strategy for cutting benzodiazepine use in general practice.
作者信息
Cormack M A, Sweeney K G, Hughes-Jones H, Foot G A
机构信息
Department of Psychology, University of Exeter.
出版信息
Br J Gen Pract. 1994 Jan;44(378):5-8.
AIM
This study set out to assess the effect of a letter from the general practitioner, suggesting a reduction in the use of benzodiazepines, and whether the impact of the letter could be increased by the addition of information on how to tackle drug reduction.
METHOD
Two hundred and nine long-term users of benzodiazepines in general practice were divided into three groups: two intervention groups and a control group. The first intervention group received a letter from their general practitioner asking that benzodiazepine use be gradually reduced and perhaps, in time, stopped. The second intervention group received the same letter plus four information sheets at monthly intervals, designed to assist drug reduction: The mean age of the 209 people was 69 years (age range 34-102 years).
RESULTS
After six months, both intervention groups had reduced their consumption to approximately two thirds of the original intake of benzodiazepines and there was a statistically significant difference between the intervention groups and the control group. Eighteen per cent of those receiving the interventions received no prescriptions at all during the six month monitoring period.
CONCLUSION
The results indicate that a simple intervention can have a considerable effect on the use of hypnotic and anxiolytic drugs, even with a sample of elderly users.
目的
本研究旨在评估全科医生发出的建议减少苯二氮䓬类药物使用的信件的效果，以及通过增加有关如何解决药物减量问题的信息，是否能增强该信件的影响力。
方法
209名长期在全科医疗中使用苯二氮䓬类药物的患者被分为三组：两个干预组和一个对照组。第一个干预组收到全科医生的一封信，要求逐渐减少苯二氮䓬类药物的使用，并可能最终停用。第二个干预组收到同样的信件，外加每月一份旨在协助药物减量的资料单。这209人的平均年龄为69岁（年龄范围34 - 102岁）。
结果
六个月后，两个干预组的药物消耗量均降至原来苯二氮䓬类药物摄入量的约三分之二，干预组与对照组之间存在统计学上的显著差异。在六个月的监测期内，接受干预的患者中有18%完全没有收到处方。
结论
结果表明，即使是针对老年使用者样本，一项简单的干预措施也能对催眠药和抗焦虑药的使用产生相当大的影响。
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