Naughton B A, Kaplan S M, Roy M, Burdowski A J, Gordon A S, Piliero S J
Science. 1977 Apr 15;196(4287):301-2. doi: 10.1126/science.847471.
The regenerating liver produces erythropoietin in response to hypoxia. The amounts of erythropoietin produced in animals subjected to hepatectomy are significantly higher than those observed in sham-operated animals. Hepatic erythropoietin production appears to be dependent upon the stage of regeneration with the highest levels being produced during the period of greatest proliferation and increase in liver mass.
再生肝在缺氧时会产生促红细胞生成素。接受肝切除术的动物产生的促红细胞生成素量明显高于假手术动物。肝脏促红细胞生成素的产生似乎取决于再生阶段，在肝脏质量最大增殖和增加的时期产生的水平最高。
