Linn S, Carroll M, Johnson C, Fulwood R, Kalsbeek W, Briefel R
Division of Health Examination Statistics, National Center for Health Statistics, Hyattsville, Md.
Am J Public Health. 1993 Jun;83(6):811-6. doi: 10.2105/ajph.83.6.811.
High-density lipoprotein (HDL) cholesterol is known to be positively related to moderate alcohol consumption from studies in selected populations. This study describes the association in a representative sample of the US adult population.
Stratification and multivariate regression analyses were used to examine HDL cholesterol levels and alcohol consumption.
Fewer women than men reported consumption of alcohol at any frequency. Similar percentages of Whites and Blacks reported alcohol consumption. Age-adjusted mean HDL cholesterol levels were higher among alcohol drinkers than among nondrinkers in all sex-race strata. Mean HDL cholesterol levels of Whites and Blacks of both sexes increased consistently with increased frequency of consumption of beer, wine, and liquor. With age, education, body mass index, smoking, and physical activity controlled for, there were higher age-adjusted HDL cholesterol levels with increasing reported quantities of alcohol consumed. Daily or weekly use of alcohol led to an increase of 5.1 mg/dL in mean HDL cholesterol level, whereas consumption of 1 g of alcohol led to an increase of 0.87 mg/dL.
Even if there is a causal association between alcohol consumption and higher HDL cholesterol levels, it is suggested that efforts to reduce coronary heart disease risks concentrate on the cessation of smoking and weight control.
从特定人群的研究中可知，高密度脂蛋白（HDL）胆固醇与适度饮酒呈正相关。本研究描述了美国成年人群代表性样本中的这种关联。
采用分层和多变量回归分析来研究HDL胆固醇水平与饮酒情况。
报告任何饮酒频率的女性都比男性少。白人和黑人报告饮酒的比例相似。在所有性别 - 种族分层中，经年龄调整后，饮酒者的HDL胆固醇平均水平高于不饮酒者。男女白人和黑人的HDL胆固醇平均水平均随着啤酒、葡萄酒和烈酒饮用频率的增加而持续上升。在控制了年龄、教育程度、体重指数、吸烟和身体活动后，随着报告的饮酒量增加，经年龄调整后的HDL胆固醇水平更高。每日或每周饮酒会使HDL胆固醇平均水平增加5.1mg/dL，而摄入1g酒精会使HDL胆固醇水平增加0.87mg/dL。
即使饮酒与较高的HDL胆固醇水平之间存在因果关联，但仍建议降低冠心病风险的努力应集中在戒烟和控制体重上。
