Partonen T, Appelberg B, Partinen M
Ullanlinna Sleep Disorders Clinic and Research Centre, Helsinki, Finland.
Eur Arch Psychiatry Clin Neurosci. 1993;242(5):310-3. doi: 10.1007/BF02190391.
Twelve outpatients with seasonal affective disorder (depression, winter type) were treated by 1 h of bright light exposure for five mornings. The intervention produced a significant reduction in depression scores, but no change was seen in the sleep electroencephalographic variables recorded after light treatment. Significant changes were seen, however, in ratings of subjective sleepiness. The acrophase of the circadian sleepiness rhythm was phase advanced, the mean level of the sleepiness rhythm was diminished, and the mean values of sleepiness scores were reduced at 8 and 10 a.m. This minimal influence of bright light on sleep structure is unlikely to explain the well-documented antidepressant effect.
12名季节性情感障碍（冬季型抑郁症）门诊患者接受了为期五个上午、每次1小时的强光照射治疗。该干预措施使抑郁评分显著降低，但光照治疗后记录的睡眠脑电图变量未见变化。然而，主观嗜睡评分出现了显著变化。昼夜嗜睡节律的高峰相位提前，嗜睡节律的平均水平降低，上午8点和10点的嗜睡评分平均值下降。强光对睡眠结构的这种微小影响不太可能解释已充分证明的抗抑郁作用。
