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英国心血管疾病死亡率的种族差异:在糖尿病患者中这些差异依然存在吗?

Ethnic differences in mortality from cardiovascular disease in the UK: do they persist in people with diabetes?

作者信息

Chaturvedi N, Fuller J H

机构信息

Department of Epidemiology and Public Health, University College London.

出版信息

J Epidemiol Community Health. 1996 Apr;50(2):137-9. doi: 10.1136/jech.50.2.137.

Abstract

STUDY OBJECTIVE

To determine whether ethnic differences in cardiovascular disease mortality persist in people with non-insulin-dependent diabetes mellitus.

DESIGN

This was an ecological study in which routine mortality data from 1985-86, which coded all mentioned causes of death, provided the numerator. The UK population derived from 1981 census formed the denominator.

SETTING

United Kingdom.

PARTICIPANTS

Records of all deaths in people aged 45 years and above were extracted if diabetes was mentioned anywhere on the death certificate. The denominator was aged five years to approximate to the 1986 population. Mortality rates where a cardiovascular underlying cause was given were compared between South Asians, African-Caribbeans, and those born in England and Wales. The latter group formed the standard for directly standardised rate ratios.

MAIN RESULTS

Mortality from heart disease was approximately three times higher in diabetic South Asian born men and women than in those with diabetes born in England and Wales. This ethnic difference was greatest in the younger age group. Conversely, stroke mortality rates in African-Caribbeans were 3.5-4 times higher than those in the England and Wales population. Despite this high mortality from stroke, ischaemic heart disease death rates were not high in African-Caribbean men.

CONCLUSIONS

Ethnic differences in cardiovascular mortality persisted and were greater in those with diabetes. Thus the high risk of heart disease should be targeted for intervention in South Asians, and the high rates of stroke targeted in African-Caribbeans.

摘要

研究目的

确定非胰岛素依赖型糖尿病患者中心血管疾病死亡率的种族差异是否持续存在。

设计

这是一项生态学研究,其中1985 - 1986年的常规死亡率数据(对所有提及的死亡原因进行编码)作为分子。1981年人口普查得出的英国人口作为分母。

背景

英国。

参与者

如果死亡证明上任何地方提及糖尿病,则提取所有45岁及以上人群的死亡记录。分母年龄为五岁,以接近1986年的人口情况。比较南亚人、非洲裔加勒比人和出生在英格兰及威尔士的人中心血管疾病作为潜在死因的死亡率。后一组作为直接标准化率比的标准。

主要结果

出生于南亚的糖尿病男性和女性的心脏病死亡率比出生在英格兰及威尔士的糖尿病患者高出约三倍。这种种族差异在较年轻年龄组中最为明显。相反,非洲裔加勒比人的中风死亡率比英格兰及威尔士人群高出3.5至4倍。尽管中风死亡率很高,但非洲裔加勒比男性的缺血性心脏病死亡率并不高。

结论

心血管疾病死亡率的种族差异持续存在,且在糖尿病患者中更为明显。因此,应针对南亚人的心脏病高风险进行干预,针对非洲裔加勒比人的高中风率进行干预。

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