Gomborone J E, Gorard D A, Dewsnap P A, Libby G W, Farthing M J
Digestive Diseases Research Centre, St Bartholomew's, London.
J R Coll Physicians Lond. 1996 Nov-Dec;30(6):512-3.
The aetiologies of irritable bowel syndrome and chronic fatigue are unknown. Psychological as well as physical factors have been implicated in both. Fatigue is common in irritable bowel syndrome patients. The purpose of the study was to determine the prevalence of irritable bowel syndrome in chronic fatigue sufferers. A bowel symptom questionnaire was sent to all 4,000 members of a self-help group for fatigue sufferers. Of the 1,797 who responded, 1,129 (63%) fulfilled a diagnosis of irritable bowel syndrome (recurrent abdominal pain and at least three Manning criteria). This greatly exceeds estimates of irritable bowel syndrome prevalence of up to 22% in the general population. Furthermore, irritable bowel syndrome sufferers within this chronic fatigue population reported more Manning criteria (14% had all six Manning criteria) than irritable bowel syndrome sufferers in the general population. This study demonstrates an overlap of symptoms in chronic fatigue and irritable bowel syndrome. In chronic fatigue, irritable bowel symptoms may be one aspect of a more generalised disorder.
肠易激综合征和慢性疲劳的病因尚不清楚。心理因素和身体因素都与之相关。疲劳在肠易激综合征患者中很常见。该研究的目的是确定慢性疲劳患者中肠易激综合征的患病率。一份肠道症状问卷被发送给一个疲劳患者自助小组的所有4000名成员。在1797名回复者中，1129人（63%）符合肠易激综合征的诊断标准（反复腹痛且至少满足三项曼宁标准）。这大大超过了一般人群中肠易激综合征患病率高达22%的估计。此外，在这个慢性疲劳人群中的肠易激综合征患者比一般人群中的肠易激综合征患者报告了更多的曼宁标准（14%的人满足所有六项曼宁标准）。这项研究表明慢性疲劳和肠易激综合征存在症状重叠。在慢性疲劳中，肠易激症状可能是一种更广泛疾病的一个方面。
