Perspectives series: host/pathogen interactions. Dynamics of HIV-1 replication in vivo.
作者信息
Ho D D
机构信息
Aaron Diamond AIDS Research Center, The Rockefeller University, New York 10016, USA.
出版信息
J Clin Invest. 1997 Jun 1;99(11):2565-7. doi: 10.1172/JCI119443.
Abstract
摘要
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2
Prognosis in HIV-1 infection predicted by the quantity of virus in plasma.根据血浆中病毒数量预测的HIV-1感染预后。
Science. 1996 May 24;272(5265):1167-70. doi: 10.1126/science.272.5265.1167.
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Viral counts count in HIV infection.病毒载量在HIV感染中很重要。
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HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time.体内HIV-1动态变化：病毒体清除率、受感染细胞寿命及病毒生成时间。
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HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease.在疾病的临床潜伏期，HIV感染在淋巴组织中活跃且呈进行性发展。
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