McKee T C, Bokesch H R, McCormick J L, Rashid M A, Spielvogel D, Gustafson K R, Alavanja M M, Cardelline J H, Boyd M R
Laboratory of Drug Discovery Research and Development, National Cancer Institute, Frederick, Maryland 21702-1201, USA.
J Nat Prod. 1997 May;60(5):431-8. doi: 10.1021/np970031g.
New cytotoxic isomalabaricane triterpenes have been isolated from a sponge Stelletta sp. (1-7); anti-HIV pterocarpans (8 and 9) and isoflavanoids (12-16 and 18) were elucidated from two tropical plants in the genus Erythrina; and anti-HIV enniatins (20 and 22-23) were characterized from fungi in the genera Fusarium and Alternaria. The enniatins were evaluated for in vivo anti-HIV activity in the hollow fiber assay.
新的细胞毒性异马拉巴烷三萜已从一种海绵（Stelletta sp.）中分离出来（1 - 7）；从刺桐属的两种热带植物中阐明了抗HIV紫檀烷（8和9）和异黄酮（12 - 16和18）；并且从镰刀菌属和链格孢属的真菌中鉴定出了抗HIV恩镰孢菌素（20和22 - 23）。在中空纤维试验中评估了恩镰孢菌素的体内抗HIV活性。
