Spray S B, Zuidema G D, Cameron J L
Am J Surg. 1976 Jun;131(6):701-3. doi: 10.1016/0002-9610(76)90181-1.
Aspiration has been suggested as a source of pulmonary complications seen in patients with tracheal intubation. A previous study demonstrated that the high incidence of aspiration in patients with tracheostomies can be decreased by modification of the tracheostomy tube cuff design. In the present protocol, 100 patients with endotracheal tubes in place were studied to document the incidence of aspiration and to attempt to decrease the incidence by modification of cuff design. Utilizing an Evans blue dye test to detect aspiration, 27 of the 48 patients (56%) with standard low volume, high pressure cuffed tubes had positive tests. In 17 patients with modified standard cuffed tubes, the incidence of aspiration was decreased to 29% (5 patients). Aspiration was further decreased to 20% (7 patients) in the 35 patients with high volume, low pressure cuffed tubes. These results demonstrate that the incidence of aspiration in patients with endotracheal tubes can be decreased by modification of endotracheal tube cuff design.
误吸被认为是气管插管患者出现肺部并发症的一个原因。先前的一项研究表明，通过改良气管造口管的套囊设计，可以降低气管造口患者误吸的高发生率。在本方案中，对100例留置气管内导管的患者进行了研究，以记录误吸的发生率，并试图通过改良套囊设计来降低发生率。利用伊文思蓝染料试验来检测误吸情况，48例使用标准小容量、高压套囊导管的患者中有27例（56%）试验呈阳性。在17例使用改良标准套囊导管的患者中，误吸发生率降至29%（5例）。在35例使用大容量、低压套囊导管的患者中，误吸进一步降至20%（7例）。这些结果表明，通过改良气管内导管套囊设计，可以降低气管内导管患者的误吸发生率。
