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1
DNA sequence variation within vanA, vanB, vanC-1, and vanC-2/3 genes of clinical Enterococcus isolates.临床肠球菌分离株的vanA、vanB、vanC-1和vanC-2/3基因内的DNA序列变异。
Antimicrob Agents Chemother. 1998 Jan;42(1):202-5. doi: 10.1128/AAC.42.1.202.
2
Multiplex PCR detection of vanA, vanB, vanC-1, and vanC-2/3 genes in enterococci.肠球菌中vanA、vanB、vanC-1和vanC-2/3基因的多重聚合酶链反应检测
J Clin Microbiol. 1997 Mar;35(3):703-7. doi: 10.1128/jcm.35.3.703-707.1997.
3
The vanB gene of vancomycin-resistant Enterococcus faecalis V583 is structurally related to genes encoding D-Ala:D-Ala ligases and glycopeptide-resistance proteins VanA and VanC.耐万古霉素粪肠球菌V583的vanB基因在结构上与编码D-丙氨酸：D-丙氨酸连接酶以及糖肽抗性蛋白VanA和VanC的基因相关。
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Analysis of genes encoding D-alanine-D-alanine ligase-related enzymes in Enterococcus casseliflavus and Enterococcus flavescens.格氏肠球菌和微黄肠球菌中编码D-丙氨酸-D-丙氨酸连接酶相关酶的基因分析
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7
Sequence of the vanB and ddl genes encoding D-alanine:D-lactate and D-alanine:D-alanine ligases in vancomycin-resistant Enterococcus faecalis V583.耐万古霉素粪肠球菌V583中编码D-丙氨酸：D-乳酸酯连接酶和D-丙氨酸：D-丙氨酸连接酶的vanB和ddl基因序列。
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Sequence of the vanC gene of Enterococcus gallinarum BM4174 encoding a D-alanine:D-alanine ligase-related protein necessary for vancomycin resistance.鹑鸡肠球菌BM4174的vanC基因序列，该基因编码一种对万古霉素耐药性必需的D-丙氨酸：D-丙氨酸连接酶相关蛋白。
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Genotypic diversity, antimicrobial resistance, and virulence factors of human isolates and probiotic cultures constituting two intraspecific groups of Enterococcus faecium isolates.构成粪肠球菌分离株两个种内组的人类分离株和益生菌培养物的基因型多样性、抗菌药物耐药性及毒力因子
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Evaluation of the AdvanDx VRE EVIGENE assay for detection of vanA in vancomycin-resistant Staphylococcus aureus.评估AdvanDx VRE EVIGENE检测法用于检测耐万古霉素金黄色葡萄球菌中的vanA基因。
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Antimicrob Agents Chemother. 2006 Mar;50(3):1054-62. doi: 10.1128/AAC.50.3.1054-1062.2006.

本文引用的文献

1
Multiplex PCR detection of vanA, vanB, vanC-1, and vanC-2/3 genes in enterococci.肠球菌中vanA、vanB、vanC-1和vanC-2/3基因的多重聚合酶链反应检测
J Clin Microbiol. 1997 Mar;35(3):703-7. doi: 10.1128/jcm.35.3.703-707.1997.
2
In vivo development of teicoplanin resistance in a VanB Enterococcus faecium isolate.一株VanB型屎肠球菌中替考拉宁耐药性的体内演变
J Infect Dis. 1993 May;167(5):1224-7. doi: 10.1093/infdis/167.5.1224.
3
The vanB gene of vancomycin-resistant Enterococcus faecalis V583 is structurally related to genes encoding D-Ala:D-Ala ligases and glycopeptide-resistance proteins VanA and VanC.耐万古霉素粪肠球菌V583的vanB基因在结构上与编码D-丙氨酸：D-丙氨酸连接酶以及糖肽抗性蛋白VanA和VanC的基因相关。
Gene. 1993 Feb 14;124(1):143-4. doi: 10.1016/0378-1119(93)90779-3.
4
A gene conferring resistance to vancomycin but not teicoplanin in isolates of Enterococcus faecalis and Enterococcus faecium demonstrates homology with vanB, vanA, and vanC genes of enterococci.在粪肠球菌和屎肠球菌分离株中发现的一种赋予对万古霉素而非替考拉宁耐药性的基因，与肠球菌的vanB、vanA和vanC基因具有同源性。
Antimicrob Agents Chemother. 1993 Aug;37(8):1604-9. doi: 10.1128/AAC.37.8.1604.
5
Sequence of the vanB and ddl genes encoding D-alanine:D-lactate and D-alanine:D-alanine ligases in vancomycin-resistant Enterococcus faecalis V583.耐万古霉素粪肠球菌V583中编码D-丙氨酸：D-乳酸酯连接酶和D-丙氨酸：D-丙氨酸连接酶的vanB和ddl基因序列。
Gene. 1994 Mar 11;140(1):97-102. doi: 10.1016/0378-1119(94)90737-4.
6
Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing.解读脉冲场凝胶电泳产生的染色体DNA限制性图谱：细菌菌株分型标准
J Clin Microbiol. 1995 Sep;33(9):2233-9. doi: 10.1128/jcm.33.9.2233-2239.1995.
7
Inducible and constitutive expression of vanC-1-encoded resistance to vancomycin in Enterococcus gallinarum.鹑鸡肠球菌中vanC-1编码的对万古霉素的抗性的可诱导性和组成型表达。
Antimicrob Agents Chemother. 1995 Jul;39(7):1480-4. doi: 10.1128/AAC.39.7.1480.

临床肠球菌分离株的vanA、vanB、vanC-1和vanC-2/3基因内的DNA序列变异。

DNA sequence variation within vanA, vanB, vanC-1, and vanC-2/3 genes of clinical Enterococcus isolates.

作者信息

Patel R, Uhl J R, Kohner P, Hopkins M K, Steckelberg J M, Kline B, Cockerill F R

机构信息

Division of Clinical Microbiology, Mayo Clinic and Foundation, Rochester, Minessota 55902, USA.

出版信息

Antimicrob Agents Chemother. 1998 Jan;42(1):202-5. doi: 10.1128/AAC.42.1.202.

DOI:10.1128/AAC.42.1.202
PMID:9449290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC105485/
Abstract

We studied the DNA sequence variation of van genes of 34 isolates of Enterococcus spp. The isolates containing the vanB gene exhibited between 0 and 41 base pair changes per 801 bp studied when the vanB sequences were compared to that of the reference strain Enterococcus faecalis V583. The isolates carrying the vanC-2 gene exhibited between 0 and 23 base pair changes per 346 bp studied when the vanC-2 sequences were compared to that of the reference strain E. casseliflavus ATCC 25788. Little variation was noted in the vanA and vanC-1 genes.

摘要

我们研究了34株肠球菌属菌株van基因的DNA序列变异情况。当将含有vanB基因的菌株的vanB序列与参考菌株粪肠球菌V583的序列进行比较时，在所研究的801 bp中，每801 bp碱基对变化为0至41个。当将携带vanC - 2基因的菌株的vanC - 2序列与参考菌株格氏肠球菌ATCC 25788的序列进行比较时，在所研究的346 bp中，每346 bp碱基对变化为0至23个。vanA和vanC - 1基因的变异较小。