临床肠球菌分离株的vanA、vanB、vanC-1和vanC-2/3基因内的DNA序列变异。
DNA sequence variation within vanA, vanB, vanC-1, and vanC-2/3 genes of clinical Enterococcus isolates.
作者信息
Patel R, Uhl J R, Kohner P, Hopkins M K, Steckelberg J M, Kline B, Cockerill F R
机构信息
Division of Clinical Microbiology, Mayo Clinic and Foundation, Rochester, Minessota 55902, USA.
出版信息
Antimicrob Agents Chemother. 1998 Jan;42(1):202-5. doi: 10.1128/AAC.42.1.202.
Abstract
We studied the DNA sequence variation of van genes of 34 isolates of Enterococcus spp. The isolates containing the vanB gene exhibited between 0 and 41 base pair changes per 801 bp studied when the vanB sequences were compared to that of the reference strain Enterococcus faecalis V583. The isolates carrying the vanC-2 gene exhibited between 0 and 23 base pair changes per 346 bp studied when the vanC-2 sequences were compared to that of the reference strain E. casseliflavus ATCC 25788. Little variation was noted in the vanA and vanC-1 genes.
摘要
我们研究了34株肠球菌属菌株van基因的DNA序列变异情况。当将含有vanB基因的菌株的vanB序列与参考菌株粪肠球菌V583的序列进行比较时，在所研究的801 bp中，每801 bp碱基对变化为0至41个。当将携带vanC - 2基因的菌株的vanC - 2序列与参考菌株格氏肠球菌ATCC 25788的序列进行比较时，在所研究的346 bp中，每346 bp碱基对变化为0至23个。vanA和vanC - 1基因的变异较小。
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本文引用的文献
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J Clin Microbiol. 1997 Mar;35(3):703-7. doi: 10.1128/jcm.35.3.703-707.1997.
2
In vivo development of teicoplanin resistance in a VanB Enterococcus faecium isolate.一株VanB型屎肠球菌中替考拉宁耐药性的体内演变
J Infect Dis. 1993 May;167(5):1224-7. doi: 10.1093/infdis/167.5.1224.
3
The vanB gene of vancomycin-resistant Enterococcus faecalis V583 is structurally related to genes encoding D-Ala:D-Ala ligases and glycopeptide-resistance proteins VanA and VanC.耐万古霉素粪肠球菌V583的vanB基因在结构上与编码D-丙氨酸：D-丙氨酸连接酶以及糖肽抗性蛋白VanA和VanC的基因相关。
Gene. 1993 Feb 14;124(1):143-4. doi: 10.1016/0378-1119(93)90779-3.
4
A gene conferring resistance to vancomycin but not teicoplanin in isolates of Enterococcus faecalis and Enterococcus faecium demonstrates homology with vanB, vanA, and vanC genes of enterococci.在粪肠球菌和屎肠球菌分离株中发现的一种赋予对万古霉素而非替考拉宁耐药性的基因，与肠球菌的vanB、vanA和vanC基因具有同源性。
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5
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