Sarsfield J K, Boyle A G, Rowell E M, Moriarty S C
Arch Dis Child. 1976 Mar;51(3):186-9. doi: 10.1136/adc.51.3.186.
A history of pet contact and/or apparent clinical sensitivity was obtained in 65 (55%) of 118 unselected asthmatic children. These 65 children were skin tested and their sera examined for specific IgE using the radioallergosorbent test. Those children who had apparent clinical sensitivities had larger skin test reactions and were more likely to have positive specific IgE results than those without apparent sensitivities. Positive skin tests were very common (80%), but the larger the skin test reaction (weal diameter greater than 4 mm diameter) the more likely was there to be a positive history or a positive specific IgE result. Hence a large skin test reaction can provide a helpful pointer to animal allergy of clinical importance. Commercially available animal extracts have limitations for diagnostic tests. A questionnaire survey of 150 day schools emphasized the potential opportunities for contact with animal allergens at school.
在118名未经挑选的哮喘儿童中，65名（55%）有宠物接触史和/或明显的临床过敏反应。对这65名儿童进行了皮肤试验，并使用放射变应原吸附试验检测他们血清中的特异性IgE。与没有明显过敏反应的儿童相比，那些有明显临床过敏反应的儿童皮肤试验反应更大，特异性IgE结果呈阳性的可能性也更高。阳性皮肤试验非常常见（80%），但皮肤试验反应越大（风团直径大于4毫米），有阳性病史或特异性IgE结果呈阳性的可能性就越大。因此，大的皮肤试验反应可为具有临床重要性的动物过敏提供有用的线索。市售的动物提取物在诊断测试方面存在局限性。对150所日间学校的问卷调查强调了在学校接触动物过敏原的潜在机会。
