Weber H, Chételat A, Caldelari D, Farmer E E
Laboratory of Plant Biology and Physiology, Biology Building, University of Lausanne-Dorigny, 1015 Lausanne, Switzerland.
Plant Cell. 1999 Mar;11(3):485-94. doi: 10.1105/tpc.11.3.485.
We conducted a study of the patterns and dynamics of oxidized fatty acid derivatives (oxylipins) in potato leaves infected with the late-blight pathogen Phytophthora infestans. Two 18-carbon divinyl ether fatty acids, colneleic acid and colnelenic acid, accumulated during disease development. To date, there are no reports that such compounds have been detected in higher plants. The divinyl ether fatty acids accumulate more rapidly in potato cultivar Matilda (a cultivar with increased resistance to late blight) than in cultivar Bintje, a susceptible cultivar. Colnelenic acid reached levels of up to approximately 24 nmol (7 microgram) per g fresh weight of tissue in infected leaves. By contrast, levels of members of the jasmonic acid family did not change significantly during pathogenesis. The divinyl ethers also accumulated during the incompatible interaction of tobacco with tobacco mosaic virus. Colneleic and colnelenic acids were found to be inhibitory to P. infestans, suggesting a function in plant defense for divinyl ethers, which are unstable compounds rarely encountered in biological systems.
我们对感染晚疫病病原体致病疫霉的马铃薯叶片中氧化脂肪酸衍生物（氧脂素）的模式和动态进行了研究。在病害发展过程中，两种18碳二乙烯基醚脂肪酸——科内列酸和科内列烯酸积累。迄今为止，尚无在高等植物中检测到此类化合物的报道。二乙烯基醚脂肪酸在马铃薯品种马蒂尔达（一个对晚疫病抗性增强的品种）中比在感病品种宾杰中积累得更快。在感染叶片中，科内列烯酸达到每克鲜重组织约24纳摩尔（7微克）的水平。相比之下，茉莉酸家族成员的水平在发病过程中没有显著变化。二乙烯基醚在烟草与烟草花叶病毒的不亲和互作过程中也会积累。已发现科内列酸和科内列烯酸对致病疫霉有抑制作用，这表明二乙烯基醚在植物防御中发挥作用，而二乙烯基醚是生物系统中很少遇到的不稳定化合物。
