Ouwehand A C, Isolauri E, Kirjavainen P V, Tölkko S, Salminen S J
Department of Biochemistry and Food Chemistry, University of Turku, Finland.
Lett Appl Microbiol. 2000 Jan;30(1):10-3. doi: 10.1046/j.1472-765x.2000.00590.x.
The ability to adhere to mucosal surfaces is related to many probiotic health effects. In the presence of Lactobacillus GG or Lact. bulgaricus, the adhesion of Bifidobacterium lactis Bb12 to a mucus model was more than doubled. Other tested lactobacilli did not affect the adhesion, nor was the adhesion of the lactobacilli influenced by the bifidobacteria. Co-aggregation between Bif. lactis Bb12 and the tested lactobacilli was insignificant and does not explain the observed effect. The results suggest that combinations of probiotics strains may have synergistic adhesion effects. Such specific strain combinations should also be assessed in clinical studies.
黏附于黏膜表面的能力与许多益生菌的健康功效相关。在存在鼠李糖乳杆菌GG或保加利亚乳杆菌的情况下，乳酸双歧杆菌Bb12对黏液模型的黏附力增加了一倍多。其他测试的乳酸杆菌未影响黏附力，乳酸杆菌的黏附力也不受双歧杆菌的影响。乳酸双歧杆菌Bb12与测试的乳酸杆菌之间的共聚集不显著，无法解释观察到的效果。结果表明，益生菌菌株组合可能具有协同黏附作用。这种特定的菌株组合也应在临床研究中进行评估。
