Serum concentration measurements in man of the radiosensitizer Ro-07-0582: some preliminary results.
作者信息
Foster J L, Flockhart I R, Dische S, Gray A, Lenox-Smith I, Smithen C E
出版信息
Br J Cancer. 1975 Jun;31(6):679-83. doi: 10.1038/bjc.1975.115.
Abstract
摘要
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Serum concentration measurements in man of the radiosensitizer Ro-07-0582: some preliminary results.放射增敏剂Ro-07-0582在人体中的血清浓度测量：一些初步结果。
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Lack of stereoselectivity in the pharmacokinetics and metabolism of the radiosensitizer Ro 03-8799 in man.放射增敏剂Ro 03-8799在人体药代动力学和代谢过程中缺乏立体选择性。
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Hypoxic cell radiosensitizers and local control by X-ray of a transplanted tumour in mice.缺氧细胞放射增敏剂与小鼠移植瘤的X射线局部控制
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Clinical testing of the radiosensitizer Ro 07-0582: experience with multiple doses.放射增敏剂Ro 07-0582的临床试验：多次给药的经验
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Pharmacokinetic considerations in testing hypoxic cell radiosensitizers in mouse tumours.在小鼠肿瘤中测试乏氧细胞放射增敏剂时的药代动力学考量
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Clinical studies with misonidazole.米索硝唑的临床研究。
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The hypoxic cell sensitizer programme in the United States.美国的低氧细胞增敏剂项目。
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Some aspects of the metabolism of misonidazole.米索硝唑代谢的某些方面。
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Radiosensitization by misonidazole (Ro-07-0582) of fractionated X-rays in a murine tumour.米索硝唑（Ro-07-0582）对小鼠肿瘤分次X射线的放射增敏作用。
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Absorptiometric, polarographic, and gas chromatographic assays for the determination of N-1-substituted nitroimidazoles in blood and urine.用于测定血液和尿液中N-1-取代硝基咪唑的吸光光度法、极谱法和气相色谱法。
J Pharm Sci. 1970 Feb;59(2):201-10. doi: 10.1002/jps.2600590213.
4
Demonstration of radiosensitization of hypoxic cells in solid tumours by metronidazole.甲硝唑对实体瘤缺氧细胞放射增敏作用的证明。
Br J Radiol. 1974 Jul;47(559):399-404. doi: 10.1259/0007-1285-47-559-399.
5
Letter: "High-dose" metronidazole: a preliminary pharmacological study prior to its investigational use in clinical radiotherapy trials.信函：“高剂量”甲硝唑：在临床放射治疗试验中进行研究性使用之前的初步药理学研究。
Br J Radiol. 1974 May;47(557):297-9. doi: 10.1259/0007-1285-47-557-297-c.
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A model system for the evaluation of the role of cholesterol -oxide in ultraviolet carcinogenesis.用于评估胆固醇氧化物在紫外线致癌作用中角色的模型系统。
Cancer Res. 1972 Dec;32(12):2630-2.
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Metronidazole ("Flagyl"). A radiosensitizer of hypoxic cells.甲硝唑（“灭滴灵”）。一种缺氧细胞的放射增敏剂。
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Radiosensitization of anoxic cells by metronidazole.甲硝唑对缺氧细胞的放射增敏作用。
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Radiology. 1974 Nov;113(2):441-4. doi: 10.1148/113.2.441.
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