Tavani A, Gallus S, Bosetti C, Tzonou A, Lagiou P, Negri E, Trichopoulos D, La Vecchia C
Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milan, Italy.
Eur J Cancer Prev. 2002 Apr;11(2):125-8. doi: 10.1097/00008469-200204000-00003.
The relation between diabetes and prostate cancer risk was investigated in a combined analysis of two hospital-based case-control studies conducted in Italy and Greece, between 1985 and 1997. Cases were 608 men with incident prostate cancer, and controls were 1008 men admitted to hospital for acute non-neoplastic diseases. No material association between diabetes and prostate cancer was observed, with a multivariate odds ratio (OR) of 1.07 (95% confidence interval (CI) 0.68-1.66). Compared with men without diabetes, there was a non-significant increased risk of prostate cancer in those diagnosed with diabetes within the last 5 years (OR 2.04), while the ORs were 0.96 and 0.78 respectively for a diagnosis of diabetes 5-9 years and > or = 10 years ago.
1985年至1997年间，在意大利和希腊开展的两项基于医院的病例对照研究的合并分析中，对糖尿病与前列腺癌风险之间的关系进行了调查。病例为608例新发前列腺癌男性患者，对照为1008例因急性非肿瘤性疾病入院的男性患者。未观察到糖尿病与前列腺癌之间存在实质性关联，多变量比值比（OR）为1.07（95%置信区间（CI）为0.68 - 1.66）。与无糖尿病男性相比，过去5年内被诊断为糖尿病的男性患前列腺癌的风险虽有增加但无统计学意义（OR为2.04），而5 - 9年前及≥10年前被诊断为糖尿病的男性的OR分别为0.96和0.78。
