Spigaglia Patrizia, Carucci Valentina, Barbanti Fabrizio, Mastrantonio Paola
Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Antimicrob Agents Chemother. 2005 Jun;49(6):2550-3. doi: 10.1128/AAC.49.6.2550-2553.2005.
Erythromycin and tetracycline resistance was analyzed in 37 Clostridium difficile clinical isolates. Strains of different clonal origins showed different erythromycin and tetracycline resistance determinants and different genetic arrangements of the elements. In strains of recent isolation, the presence of Tn916-like elements, never found before in C. difficile clinical isolates, has been demonstrated.
对37株艰难梭菌临床分离株进行了红霉素和四环素耐药性分析。不同克隆起源的菌株表现出不同的红霉素和四环素耐药决定因素以及这些元件的不同基因排列。在近期分离的菌株中,已证实存在之前在艰难梭菌临床分离株中从未发现过的Tn916样元件。